1. Physiologically-based pharmacokinetic (PBPK) modeling of IgG (PI: Balthasar)
2. Investigation of determinants of IgG distribution in the brain (PI: Balthasar)
3. PK/PD/PG/DIS Models for Etanercept Interactions with Cytokines in a Rat Model of RA (PI: Jusko)
4. Investigation of the influence of FcRn recycling on the target-mediated elimination of of anti-CEA
monoclonal antibodies in mice (PI: Balthasar)
5. Lymphatic uptake of proteins: Use of whole body fluorescence in rodent studies (PI: Morris)
6. Ultrasensitive LC/MS Quantification of Cytokines in Biological Samples (PI: Qu)
7. Investigation of the influence of Fc-gamma-R on the elimination of monoclonal antibodies (PI: Balthasar)
8. Multiscale Systems Analysis of Anti-CD20 mAb Pharmacodynamics (PI: Mager)
9. Interferon-beta Biodisposition and Effects on Osteolytic Lesions (PI: Mager)
10. FcRn in natalizumab-treated multiple sclerosis patients (PI: Ramanathan)
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