Publications — Lovell Lab

2026

W.L. Hsu, Y. Jiao, M. Hvasta, K.N. Tran, B.T. Troyer, W.C. Huang, B. Kuhlman, A. Obregon-Henao, J.F. Lovell – A point-mutated Ag85B antigen improves recombinant bacterial expression and protects mice from aerosol M. tuberculosis challenge

Y Luo, S Zhou, S Wu, H Jin, JF Lovell – Emerging strategies for advancing peptide vaccines

D. Ivanochko, K. Miura, S. Hailemariam, R. Ravichandran, Y. Song, W.C. Huang, R. Stoter, K. Teelen, G.J Van Gemert, E. M. Leaf, S. Chan, C. Men, A. Semesi, C. Shiu, R.S. MacGill, C.A. Long, M.M. Jore, N. P. King, J. F. Lovell, J.P. Julien – A stabilized tandem antigen chimera that elicits potent malaria transmission-reducing activity

C. K. Lee, J. F. Lovell, J. S. Yun, S. K. Kim, B. M. Lee, D. H. Ha, J. Y. Lee, C. G. Lee, Y. R. Lee, W. C. Huang, J. Han – Vaccine composition for chickenpox or Varicella Zoster and method of using same

T Xu, J Huang, Y Liu, L Lu, JF Lovell, M Zhu, H Jin – A machine learning-defined cellular senescence signature systematically enhances prognostication and guides immunotherapy strategies for the treatment of gliomas

M Petion, J Lovell, Y Song, S Zhou, MD Hicar – P-1474. Development of an HIV vaccine based on 2C6, an antibody that targets a conformational gp41 epitope with cross-clade recognition and robust antibody dependent cell cytotoxicity

R Prasad, U Chitgupi, SK Metkar, JF Lovell – Chapter 21 - Optotheranostics for cancer

2025

CL Dai, Y Song, Y Chen, YC Tung, WC Huang, CX Gong, JF Lovell – Therapeutic nanoliposome vaccine targeting multiple Aβ and tau epitopes reduces AD-like brain pathologies and rescues cognitive deficits in 3xTg-AD mice

Song Y., Deng B., Long C. A., Li Q., Diakite M., Huang W. C., Zhou S., Luo Y., Ivanochko D., MacGill R. S., Julien J. P., Miura K., Lovell J. F. – Priming or Boosting Plasmodium falciparum Transmission-Blocking Responses With Recombinant Vaccines or Gametocyte Extract

Y. Cheng, C. Huang, R. W. Bing, E. Zheng, H. Zhang, W. Xu, C. Mayerl, R. German, C. M. Steele, J. F. Lovell, L. Zhang, J. Xia – Dysphagia assessment based on photoacoustic imaging: a pilot ex vivo and in vivo study in infant swine models

B. G. Morreale, A. M. Monell, H. Yu, D. B. Sykes, J. F. Lovell, M. J. Nemeth, S. I. Abrams – 693 A novel tri-therapy overcoming immune suppression, immune exhaustion, and low antigen-specific T cell infiltration elicits robust antitumor responses

Y. Jiao, S.H. Mahmoud, C. Ye, Y. Luo, W.C. Huang, Q. Li, S. Zhou, Y. Song, M. Tsuji, L. Martinez-Sobrido, J.F. Lovell – In Vivo Iterative Adjuvant Screening Identifies an Intranasal Vaccine Formulation for Elicitation of Protective Mucosal Immune Responses Against SARS-CoV-2

T. Xu, M. Yang, J. Huang, L. Lu, D. Deng, Y. Sun, J.F. Lovell, Z. Lin, Y. Zheng, H. Jin – Single-cell profiling of gastric cancer ascites reveals immunosuppressive remodeling and an epithelial-immune dual phenotype signature predictive for PD-1 immunotherapy responses

L Lu, M Yang, D Deng, X Shi, JF Lovell, H Jin – Nanovaccines: Antigen selection, stabilization, adjuvantation, formulation, and evaluation

Y. Luo, Q. Li, S. Zhou, H. Oh, J. Jablonski, Y. Song, Y. Sun, Y. Wu, H. Zhu, J. Ortega, J. F. Lovell – Lipid nanoparticles that co-deliver poly(I:C) and short peptide antigens elicit anti-tumor responses with vaccination

M Yang, S Wu, J Zhang, L Lu, D Deng, Q Xia, JF Lovell, X Shi, H Jin – Immunotherapies for Aging and Age-Related Diseases: Advances, Pitfalls, and Prospects

G Liu, H Ren, J Li, W Dong, S Li, N Zhang, C Cheng, JF Lovell, Y Zhang – Covalent organic framework eliciting a click-based intracellular copper accumulation cascade for cuproptosis cancer therapy

M. C. Mariano, M. G. Hvasta, K. A. Dowd, W-C. Huang, H. S. Jung, L. R. Evanson, G. I. Georgiev, J. C. Frei, J. F. Lovell, T. C. Pierson, B. Kuhlman, J. R. Lai – Design of Hyperglycosylated Zika Virus E Proteins that Focus Antibody Recognition on the Complex E Dimer Epitope

T Tarvirdizadeh, WC Huang, N Farizio, J Lovell, J Lang – Enhancing Cardiomyocyte Uptake of Cobalt Porphyrin-Phospholipid (CoPoP) Liposomes

H. Jin, Z. Deng, L. Lu, T. Xu, Z. Zhao, Y. Geng, L. Liu, M. Yang, Y. Zheng, J.F. Lovell, J. Ding – Enhancing Antitumor Nanovaccine Efficacy via Integrated Cholesterol Modulation In Situ

J.F. Lovell, K. Miura, Y.O. Baik, C. Lee, Y. Choi, J.Y. Lee, C. A. Long, M. Ylade, R. Lee-Llacer, N. De Asis, M. Trinidad-Aseron, J. M. Ranola, L. Zoleta De Jesus, H. Her – Year-Long Antibody Response to the EuCorVac-19 SARS-CoV-2 Vaccine in Healthy Filipinos

J. WP. Hayes, J. C. Edwards, K. Ramirez Valdez, S. Crossley, R. Fortes De Brito, D. Munir, K. Hanson, K. Paschos, K. Polra, J. An, J. G. Calvert, M. Bonnet DI PLACIDO, J.F. Lovell, R. Shattock, J.A. Hammond, R. J. Owens, S. P. Graham – Evaluation of the contribution of the minor envelope complex glycoprotein 3 to the porcine reproductive and respiratory syndrome virus 1 neutralizing antibody response

R. Ahmmed, E. Kluiszo, S. Aygun-Sunar, M. Willadsen, H. L. Kutscher, J.F. Lovell, U. Sunar – Quantitative Fluorescence Imaging of Chemophototherapy Drug Pharmacokinetics Using Laparoscopic SFDI

T. TN Phan, D. J. Thiono, M. G. Hvasta, R. P. Shah, G. Prida Ajo, W. C. Huang, J. F. Lovell, S. Tian, A. M de Silva, B. Kuhlman – Multivalent administration of dengue E dimers on liposomes elicits type-specific neutralizing responses without immune interference

X. L. Liu, X. Dong, S.C. Yang, X. Lai, H.J. Liu, Y. Gao, H.Y. Feng, M. H. Zhu, Y. Yuan, Q. Lu, J. F. Lovell, H.Z. Chen, C. Fang – Biomimetic Liposomal Nanoplatinum for Targeted Cancer Chemophototherapy

Q. Li, R. Vendramelli, T. Truong, T. Jeevan, M. Black, Y. Luo, Y. Song, W.C. Huang, S. Zhou, Y. Berhane, B.A. Davidson, R.J. Webby, D. Kobasa, J.F. Lovell – Highly pathogenic avian influenza H5N1 clade 2.3.4.4b hemagglutinin and/or neuraminidase elicit immunity in a recombinant nanoparticle vaccine

Li, R Yang, C Zhang, JF Lovell, Y Zhang – Manganese-Driven Plasmid Nanofibers Formed In Situ for Cancer Gene Delivery and Metalloimmunotherapy

B Yue, W Gao, JF Lovell, H Jin, J Huang – The cGAS-STING pathway in cancer immunity: dual roles, therapeutic strategies, and clinical challenges

S. John, Y.Y. Vaquiz, N. Nyayaoathi, L. Kabbani, A. Nilam, J.F. Lovell, N.A. Wilson, Y. Yan, M. Mehrmohammadi – Photoacoustic Imaging for Image-Guided Gastric Tube Placement: Ex Vivo Characterization

Y. Song, W.C. Huang, D. Ivanochko, C. Long, Q. Li, L. Zhou, J.P. Julien, K. Miura, J.F. Lovell – 50-Fold Adjuvant and 20-Fold Antigen Vaccine Dose Sparing from Nanoliposome Display of a Stabilized Malarial Protein Antigen

Zhang, JF Lovell, J Shi, Y Zhang – Nanomaterials for co-immobilization of multiple enzymes

Y. Yuan, Q. Lin, H.Y. Feng, Y. Zhang, X. Lai, M.H. Zhu, J. Wang, J. Shi, Y. Huang, L. Zhang, Q. Lu, Z. Yuan, J.F. Lovell, H.Z. Chen, P. Sun, C. Fang – A multistage drug delivery approach for colorectal primary tumors and lymph node metastases

J Li, R Yang, Y Yuan, H Ren, C Fang, JF Lovell, Y Zhang – An Oral Nanovaccine Secreted by Genetically Engineered and Ultrasound-Responsive Bacteria for Colon Cancer Immunotherapy

D.J. Rohrbach, K.A. Carter, D. Luo, S. Shao, S. Aygun-Sunar, J.F. Lovell U. Sunar – Fluence Rate-Dependent Kinetics of Light-Triggered Liposomal Doxorubicin Assessed by Quantitative Fluorescence-Based Endoscopic Probe

R. Prasad, A. Ghosh, V. Patel, B. Peng, B.B. Mendes, E. Honey Aung Win, L.G. Delogu, J.Y. Wong, K.J. Pischel, J.R. Bellare, A. Bar-Shir, A.S. Thakor, W.J. Parak, Z.M. Bhujwalla, Y.S. Zhang, N. Kommineni, V.M. Rotello, W. Cai, T. Lammers, T.W. Odom, G. Padmanaban, D. Peer, J.F. Lovell, R. Srivastava, R. Langer, J. Conde – Voices of Nanomedicine: Blueprint Guidelines for Collaboration in Addressing Global Unmet Medical Needs

C. Zhang, N. Zhang, R. Yang, Q. Qiu, J. Huang, J. Liu, S. Li, J.F. Lovell, H. Ren, Y. Zhang – Intracellular self-assembled nanoneedles for efficient lysosomal escape and CRISPR/Cas9 mediated gene editing

N. Kommineni, N. Kaur, GS Sainaga Jyothi Vasakuri, N. Narang, M. Mirazul Islam, P. Basim, M. Woollam, L.K. Vora, M. Agarwal, J.F. Lovell, R.P. Meena – Harnessing volatile organic compound biomarkers for early cancer detection: molecular to nanotechnology-based approaches

2024

H. Ren, Z. Wu, J. Li, N. Zhang, C.Y. Nah, J. Li, J. Zhang, J.F. Lovell, L. Zhang, Y. Zhang – A biomimetic, triggered-release micelle formulation of methotrexate and celastrol controls collagen-induced arthritis in mice

M. Yang, J. Zhou, L. Lu, D. Deng, J. Huang, Z. Tang, X. Shi, P.C. Lo, J.F. Lovell, Y. Zheng, H. Jin – Tumor cell membrane-based vaccines: A potential boost for cancer immunotherapy

Y. Song, C.L. Dai, M. Shinohara, Y. C. Tung, S. Zhou, W.C. Huang, A. Seffouh, Y. Luo, M. Willadsen, Y. Jiao, M. Morishima, Y. Saito, S.H. Koh, J. Ortega, C.X. Gong, J.F. Lovell – A pentavalent peptide vaccine elicits Aβ and tau antibodies with prophylactic activity in an Alzheimer’s disease mouse model

J. Huang, B. Yue, J. Sun, T. Xu, J. Zhou, L. Lu, Y. Yan, J.F. Lovell, C. Wan, M. Zhu, H. Jin – Injectable thermosensitive hydrogels loaded with irradiated tumor cell-derived microparticles and manganese activate anti-tumor immunity

Y. Sun, Y. Hu, Y. Geng, C. Wan, Y. Liu, Y. Liao, X. Shi, J.F. Lovell, K. Yang, H. Jin – A self-assembled, genetically engineered, irradiated tumor cell debris vaccine

K. Miura, B. Deng, R. V. Suresh, Y.T. Gebremicale, L. Zhou, T.P. Pham, K. Roche, A. Diouf, J.F. Lovell, J.P. Julien, C.A. Long – A human-serum-free medium can induce more infectious P. falciparum gametocytes than a conventional human-serum-containing medium

J.F. Lovell, K. Miura, Y.O. Barik, C. Lee, Y. Choi, H. Her, J.Y. Lee, M. Ylade, R. Lee-Llacer, N. De Asis, M. Trinidad-Aseron, J.M. Ranola, L. Zoleta De Jesus – Interim safety and immunogenicity analysis of the EuCorVac-19 COVID-19 vaccine in a Phase 3 randomized, observer-blind, immunobridging trial in the Philippines

WC Huang, WS Baker, JF Lovell, CH Schein – Displaying alphavirus physicochemical consensus antigens on immunogenic liposomes enhances antibody elicitation in mice

J. Li, R. Yang, F. Dong, Q. Qiu, Z. Jiang, H. Ren, C. Zhang, G. Liu, J.F. Lovell, Y. Zhang – Enzyme-Dynamic Extracellular Vesicles for Metalloimmunotherapy of Malignant Pleural Effusions

J.S. Kirk, J. Wang, M. Long, S. Rosario, A. Tracz, Y. Ji, R. Kumar, X. Liu, A. Jamroze, P.K. Singh, I. Puzanov, G. Chatta, Q. Cheng, J. Huang, J.L. Wrana, J. F. Lovell, H. Yu, S. Liu, M.M. Shen, T. Liu, D.G. Tang – Integrated single-cell analysis defines the epigenetic basis of castration-resistant prostate luminal cells

WC Huang, K Eberle, JR Colon, JF Lovell, H Xin – Liposomal Fba and Met6 peptide vaccination protects mice from disseminated candidiasis

C. Wang, Y. Geng, H. Wang, Z. Ren, Q. Hou, A. Fang, Q. Wu, L. Wu, X. Shi, M. Zhou, Z.F. Fu, J.F. Lovell, H. Jin, L. Zhao – A broadly applicable protein-polymer adjuvant system for antiviral vaccines

R. Prasad, V. GS Jyothi, N. Kommineni, R. T. Bulusu, B.B. Mendes, J.F. Lovell, J. Conde – Biomimetic Ghost Nanomedicine-Based Optotheranostics for Cancer

C.K. Lee, J.F. Lovell, Y.H. Whang, W.Y. Hwang, H.J. Kim, M.C. Park, S.K. Kim, W.C. Huang, D.H. Ha – Respiratory syncytial virus vaccine

Z Deng, B Li, M Yang, L Lu, X Shi, JF Lovell, X Zeng, W Hu, H Jin – Irradiated microparticles suppress prostate cancer by tumor microenvironment reprogramming and ferroptosis

S.S. Wang, S. Shao, A. Singh, R. Hombu, J.F. Lovell, K.L. Matta, S. Neelamegham – Photosensitizer-thioglycosides enhance photodynamic therapy by augmenting cellular uptake

S Zhou, Y Song, A Nilam, Y Luo, WC Huang, MD Long, JF Lovell – The predominant Quillaja Saponaria fraction, QS-18, is safe and effective when formulated in a liposomal murine cancer peptide vaccine

A. Koornneef, K. Vanshylla, G. Hardenberg, L. Rutten, N.M. Strokappe, J. Tolboom, J. Vreugdenhil, K. Feddes-de Boer, A. Perkasa, S. Blokland, J.A. Burger, W.C. Huang, J.F. Lovell, D. van Manen, R.W. Sanders, R.C. Zahn, H. Schuitemaker, J.PM. Langedijk, F. Wegmann – CoPoP liposomes displaying stabilized clade C HIV-1 Env elicit tier 2 multiclade neutralization in rabbits

S Zhou, Y Song, Y Luo, B Quinn, Y Jiao, MD Long, SI Abrams, JF Lovell – Identification of Enhanced Vaccine Mimotopes for the p15E Murine Cancer Antigen

J. Li, Q. Qiu, H. Ren, J. Zhang, C. Zhang, G. Liu, B. Sun, B. Zheng, J.F. Lovell, Y. Zhang – A metalloprotein nanoparticle scaffold co-delivers antigens and adjuvants with metal-enhanced STING activation for vaccination preventing viral infections

J Lovell, HE Xuedan, S Zhou – Formulations and methods for mhc-i restricted epitope immunization

Z.R. Sia, J. Roy, W.C. Huang, Y. Song, S. Zhou, Y. Luo, Q. Li, D. Arpin, H.L. Kutscher, J. Ortega, B.A. Davidson, J.F. Lovell – Adjuvanted nanoliposomes displaying six hemagglutinins and neuraminidases as an influenza virus vaccine

H Ren, J Li, JF Lovell, Y Zhang – Applications of Intravital Imaging in Cancer Immunotherapy

D Deng, T Hao, L Lu, M Yang, Z Zeng, JF Lovell, Y Liu, H Jin – Organic coordination nanoparticles for phototheranostics

R. Prasad, B. Peng, B.B. Mendes, H.I. Kilian, M. Gorain, H. Zhang, G.C. Kundu, J. Xia, J.F. Lovell, J. Conde – Biomimetic bright optotheranostics for metastasis monitoring and multimodal image-guided breast cancer therapeutics

Y. Jiao, W.C. Huang, K. Chiem, Y. Song, J. Sun, S.K. Chothe, S. Zhou, Y. Luo, M.T. Mabrouk, J. Ortega, S.V. Kuchipudi, L. Martinez-Sobrido, J.F. Lovell – SARS-CoV-2 Protein Nanoparticle Vaccines Formed In Situ From Lyophilized Lipids

Y. Hu, Y. Sun, Z. Liao, D. An, X. Liu, X. Yang, Y. Tian, S. Deng, J. Meng, Y. Wang, J. Li, Y. Deng, Z. Zhou, Q. Chen, Y. Ye, W. Wei, B. Wu, J.F. Lovell, H. Jin, F. Huang, C. Wan, K. Yang – Irradiated engineered tumor cell-derived microparticles remodel the tumor immune microenvironment and enhance antitumor immunity

J.F. Lovell, K. Miura, Y.O. Baik, C. Lee, J.Y. Lee, Y.S. Park, I. Hong, J.H. Lee, T. Kim, S.H. Seo, J.O. Kim, M. Song, C.J. Kim, J.K. Choi, J. Kim, E.J. Choo, J.H. Choi – One-year antibody durability induced by EuCorVac-19, a liposome-displayed COVID-19 receptor binding domain subunit vaccine, in healthy Korean subjects

2023

S Zhou, Y Luo, JF Lovell – Vaccine approaches for antigen capture by liposomes

R. He, L. Jiexin, Z. Jingyu, Y. Xingyue, Z. Nan, Q. Qian, L. Dan, Y. Yue, L. Xiaofeng, J.F. Lovell, Z. Yumiao – Anti-Tumor Immunity Induced by a Ternary Membrane System Derived From Cancer Cells, Dendritic Cells, and Bacteria

J Lovell, WC Huang – Particle based formulation of sars-cov-2 receptor binding domain

J Liu, H Ren, C Zhang, J Li, Q Qiu, N Zhang, N Jiang, JF Lovell, Y Zhang – Orally-Delivered, Cytokine-Engineered Extracellular Vesicles for Targeted Treatment of Inflammatory Bowel Disease

S. Zhou, OA Karl, M. T. Mabrouk, D. Jahagirdar, W.C. Huang, J. A. Guerra, X. He, J. Ortega, S. T Poole, E. R Hall, O. G Gomez-Duarte, M. Maciel Jr, J. F Lovell – Antibody induction in mice by liposome-displayed recombinant enterotoxigenic Escherichia coli (ETEC) colonization antigens

M. T Mabrouk, A. A Zidan, N. Aly, M. T Mohammed, F. Ghantous, M. S Seaman, J. F Lovell, M. L Nasr – Circularized Nanodiscs for Multivalent Mosaic Display of SARS-CoV-2 Spike Protein Antigens

B Sun, G Paraskevopoulos, J Min, R Rossdeutcher, S Ghosh, B Quinn, MH Lin, D Sarkar, D Sukumaran, Y Wang, K Vávrová, J F Lovell, Y Zhang – Topical Drug Delivery of Concentrated Cabazitaxel in an α-Tocopherol and DMSO Solution

U Chitgupi, Y Qin, S Ghosh, B Quinn, K Carter, X He, U Sunar, JF Lovell – Folate-Targeted Nanoliposomal Chemophototherapy

Y Yan, S John, Y Yuja Vaquiz, A Nilam, J Lovell, N Wilson, M Mehrmohammadi – Ultrasound and Photoacoustic Guided Gastrostomy to Prevent Colonic Injury

H I Kilian, H Zhang, M Mahdi Shiraz Bhurwani, A M Nilam, D Seong, M Jeon, C N Ionita, J Xia, J F Lovell – Barium sulfate and pigment admixture for photoacoustic and x-ray contrast imaging of the gut

J Meng, X Yang, JHuang, Z Tuo, Y Hu, Z Liao, Y Tian, S Deng, Y Deng, Z Zhou, J F Lovell, H Jin, Y Liu, K Yang – Ferroptosis-Enhanced Immunotherapy with an Injectable Dextran-Chitosan Hydrogel for the Treatment of Malignant Ascites in Hepatocellular Carcinoma

B Sun, J Liu, S Li, JF Lovell, Y Zhang – Imaging of Gastrointestinal Tract Ailments

S D Sonkawade, S Xu, M Kim, S Nepali, VG Karambizi, S Sexton, S G Turowski, K Li, J A Spernyak, J F Lovell, A George, S Suwal, U C Sharma, S Pokharel – Phospholipid Encapsulation of an Anti-Fibrotic Endopeptide to Enhance Cellular Uptake and Myocardial Retention

B Sun, S Shao, S Ghosh, J Li, X Wang, C Li, B Quinn, P Alexandridis, J F Lovell, Y Zhang – Facile preparation of cabazitaxel-loaded nanoparticles directly lyophilized from dioxane

MH Zhu, XD Zhu, M Long, X Lai, Y Yuan, Y Huang, L Zhang, Y Gao, J Shi, Q Lu, P Sun, J F Lovell, HZ Chen, C Fang – Metal‐Coordinated Adsorption of Nanoparticles to Macrophages for Targeted Cancer Therapy (Adv. Funct. Mater. 19/2023)

C Zhang, X Wang, G Liu, H Ren, J Li, Z Jiang, J Liu, JF Lovell, Y Zhang – Metal coordination micelles for anti-cancer treatment by gene-editing and phototherapy

MH Zhu, XD Zhu, M Long, X Lai, Y Yuan, Y Huang, L Zhang, Y Gao, J Shi, Q Lu, P Sun, J F Lovell, HZ Chen, C Fang – Metal-Coordinated Adsorption of Nanoparticles to Macrophages for Targeted Cancer Therapy

J C Hsu, Z Tang, O E Eremina, A Marios Sofias, T Lammers, J F Lovell, C Zavaleta, W Cai, D P Cormode – Nanomaterial-based contrast agents

E Oakley, M Kim, S Ghosh, H Kutscher, J Lovell, L Curtin, S Sexton, A Hutson, G Shafirstein – Interstitial chemo-phototherapy for treatment of locally advanced hepatocellular carcinoma: A preclinical study

L Lu, H Zi, J Zhou, J Huang, Z Deng, Z Tang, L Li, X Shi, PC Lo, J F Lovell, D Deng, C Wan, H Jin – Engineered Microparticles for Treatment of Murine Brain Metastasis by Reprograming Tumor Microenvironment and Inhibiting MAPK Pathway

B Sun, JF Lovell, Y Zhang – Current development of cabazitaxel drug delivery systems

S Ghosh, U Chitgupi, U Sunar, JF Lovell – Chemophototherapeutic Ablation of Doxorubicin-Resistant Human Ovarian Tumor Cells†

2022

Z Jiang, Y Ding, JF Lovell, Y Zhang – Design and application of organic contrast agents for molecular imaging in the second near infrared (NIR-II) window

H I Kilian, C Ma, H Zhang, M Chen, A Nilam, B Quinn, Y Tang, J Xia, J Yao, J F Lovell – Intraperitoneal administration for sustained photoacoustic contrast agent imaging

H Zhang, A Nagy, C Bowman, M Peladeau-Pigeon, A Hu, J Lovell, C M Steele, J Xia – Food-Grade Activated Charcoal for Contrast-Enhanced Photoacoustic Imaging of Aspiration: A Phantom Study

J F Lovell, Y O Baik, S K Choi, C Lee, JY Lee, K Miura, WC Huang, YS Park, SJ Woo, S Hwan Seo, JO Kim, M Song, CJ Kim, JK Choi, J Kim, E J Choo, JH Choi – Interim analysis from a phase 2 randomized trial of EuCorVac-19: a recombinant protein SARS-CoV-2 RBD nanoliposome vaccine

Z R Sia, K Chiem, WC Huang, A Seffouh, A T Dereshgi, T Hogan, J Ortega, B A Davidson, L Martinez-Sobrido, J F Lovell – Respiratory Vaccination with Hemagglutinin Nanoliposomes Protects Mice from Homologous and Heterologous Strains of Influenza Virus

J Li, H Ren, Q Qiu, X Yang, J Zhang, C Zhang, B Sun, JF Lovell, Y Zhang – Manganese Coordination Micelles That Activate Stimulator of Interferon Genes and Capture In Situ Tumor Antigens for Cancer Metalloimmunotherapy

B McLeod, M T Mabrouk, K Miura, R Ravichandran, S Kephart, S Hailemariam, T P Pham, A Semesi, I Kucharska, P Kundu, WC Huang, M Johnson, A Blackstone, D Pettie, M Murphy, J C Kraft, E M Leaf, Y Jiao, M Van de Vegte-Bolmer, GJ Van Gemert, J Ramjith, C Richter King, R S MacGill, Y Wu, K K Lee, M M Jore, N P King, J F Lovell, JP Julien – Vaccination with a structure-based stabilized version of malarial antigen Pfs48/45 elicits ultra-potent transmission-blocking antibody responses

WC Huang, K Chiem, L Martinez-Sobrido, JF Lovell – Intranasal Immunization with Liposome-Displayed Receptor-Binding Domain Induces Mucosal Immunity and Protection against SARS-CoV-2

S Ghosh, X He, WC Huang, JF Lovell – Immune checkpoint blockade enhances chemophototherapy in a syngeneic pancreatic tumor model

WC Huang, M T Mabrouk, L Zhou, M Baba, M Tachibana, M Torii, E Takashima, E Locke, J Plieskatt, C Richter King, C H Coelho, P E Duffy, C Long, T Tsuboi, K Miura, Y Wu, T Ishino, J F Lovell – Vaccine co-display of CSP and Pfs230 on liposomes targeting two Plasmodium falciparum differentiation stages

Z Liao, J Huang, PC Lo, JF Lovell, H Jin, K Yang – Self-adjuvanting cancer nanovaccines

S Ghosh, B Sun, D Jahagirdar, D Luo, J Ortega, R M Straubinger, J F Lovell – Single-treatment tumor ablation with photodynamic liposomal irinotecan sucrosulfate

B Sun, S Ghosh, X He, WC Huang, B Quinn, M Tian, D Jahagirdar, M T Mabrouk, J Ortega, Y Zhang, S Shao, J F Lovell – Anti-cancer liposomal chemophototherapy using bilayer-localized photosensitizer and cabazitaxel

M Li, N Beaumont, C Ma, J Rojas, T Vu, M Harlacher, G O’Connell, R C Gessner, H Kilian, L A Kasatkina, Y Chen, Q Huang, X Shen, J F Lovell, V V Verkhusha, T Czernuszewicz, J Yao – Three-Dimensional Deep-Tissue Functional and Molecular Imaging by Integrated Photoacoustic, Ultrasound, and Angiographic Tomography (PAUSAT)

Y Hu, Y Sun, C Wan, X Dai, S Wu, PC Lo, J Huang, J F Lovell, H Jin, K Yang – Microparticles: biogenesis, characteristics and intervention therapy for cancers in preclinical and clinical research

Z Tuo, Q He, Z Zhang, Y Wang, J Sun, Q Wei, Y Hu, J F Lovell, H Jin, K Yang – Irradiation conditioning of adjuvanted, autologous cancer cell membrane nanoparticle vaccines

X He, S Zhou, B Quinn, D Jahagirdar, J Ortega, M D Long, S I Abrams, J F Lovell – An In Vivo Screen to Identify Short Peptide Mimotopes with Enhanced Antitumor Immunogenicity

X Lai, XL Liu, H Pan, MH Zhu, M Long, Y Yuan, Z Zhang, X Dong, Q Lu, P Sun, J F Lovell, HZ Chen, C Fang – Light-Triggered Efficient Sequential Drug Delivery of Biomimetic Nanosystem for Multimodal Chemo-, Antiangiogenic, and Anti-MDSC Therapy in Melanoma

MT Mabrouk, WC Huang, L Martinez‐Sobrido, JF Lovell – Advanced Materials for SARS-CoV-2 Vaccines

Y Zhou, T Ye, C Ye, C Wan, S Yuan, Y Liu, T Li, F Jiang, J F Lovell, H Jin, J Chen – Secretions from hypochlorous acid-treated tumor cells delivered in a melittin hydrogel potentiate cancer immunotherapy

C Ma, H I Kilian, H Zhang, M Chen, B Quinn, Y Tang, J Xia, J F Lovell, J Yao – Deep photoacoustic imaging of a cyanine dye in the second-near-infrared window

JF Lovell – Vaccine Strategies: A Virtual Issue

K Miura, E Takashima, T P Pham, B Deng, L Zhou, WC Huang, A Diouf, Y T Gebremicale, M Tachibana, T Ishino, C Richter King, J F Lovell, C A Long, T Tsuboi – Elucidating functional epitopes within the N-terminal region of malaria transmission blocking vaccine antigen Pfs230

H Ren, J Li, G Liu, Y Sun, X Yang, Z Jiang, J Zhang, JF Lovell, Y Zhang – Anticancer Vaccination with Immunogenic Micelles That Capture and Release Pristine CD8+ T-Cell Epitopes and Adjuvants

JF Lovell – Special Issue Dedicated to Dr. Gambhir and Dr. Kircher

X Yang, Q Qiu, G Liu, H Ren, X Wang, JF Lovell, Y Zhang – Traceless antibiotic-crosslinked micelles for rapid clearance of intracellular bacteria

2021

J Lovell, S Shuai, G Jumin, WC Huang, SM Lee, CR King – Nanostructures comprising cobalt porphyrin-phospholipid conjugates and polyhistidine-tags

B Pfeifer, C Jones, J Lovell – Novel pneumococcal vaccine formulations

S Ghosh, JF Lovell – Two Laser Treatments Can Improve Tumor Ablation Efficiency of Chemophototherapy

J Li, H Ren, Y Sun, G Liu, X Yang, Q Qiu, Y Ding, JF Lovell, Y Zhang – Magnetic Metal Micelles for Enhanced Delivery of Self-Immolating CD8+ T-Cell Epitopes for Cancer Immunotherapy

J Meng, Y Li, C Wan, Y Sun, X Dai, J Huang, Y Hu, Y Gao, B Wu, Z Zhang, K Jiang, S Xu, J F Lovell, Y Hu, G Wu, H Jin, K Yang – Targeting senescence-like fibroblasts radiosensitizes non–small cell lung cancer and reduces radiation-induced pulmonary fibrosis

X He, S Zhou, M Dolan, Y Shi, J Wang, B Quinn, D Jahagirdar, WC Huang, M Tsuji, R Pili, F Ito, J Ortega, S I Abrams, J ML Ebos, J F Lovell – Immunization with short peptide particles reveals a functional CD8+ T-cell neoepitope in a murine renal carcinoma model

M T Mabrouk, K Chiem, E Rujas, WC Huang, D Jahagirdar, B Quinn, M S Nair, R H Nissly, V S Cavener, N R Boyle, T A Sornberger, S V Kuchipudi, J Ortega, JP Julien, L Martinez-Sobrido, J Lovell – Lyophilized, thermostable Spike or RBD immunogenic liposomes induce protective immunity against SARS-CoV-2 in mice

C Wan, Y Sun, Y Hu, J Huang, L Lu, Y Gao, H Zi, Q He, J Sun, J F Lovell, K Yang, H Jin – Peptide hydrogels loaded with irradiated tumor cell secretions enhance cancer immunotherapy

X He, S Zhou, B Quinn, WC Huang, D Jahagirdar, M Vega, J Ortega, M D Long, F Ito, S I Abrams, J F Lovell – Position-Scanning Peptide Libraries as Particle Immunogens for Improving CD8+ T-Cell Responses

Z Jiang, B Sun, Y Wang, H Gao, H Ren, H Zhang, T Lu, X Ren, W Wei, X Wang, L Zhang, J Li, D Ding, J F Lovell, Y Zhang – Surfactant-Stripped Micelles with Aggregation-Induced Enhanced Emission for Bimodal Gut Imaging In Vivo and Microbiota Tagging Ex Vivo

HY Feng, Y Yuan, Y Zhang, HJ Liu, X Dong, SC Yang, XL Liu, X Lai, MH Zhu, J Wang, Q Lu, Q Lin, HZ Chen, J F Lovell, P Sun, C Fang – Targeted Micellar Phthalocyanine for Lymph Node Metastasis Homing and Photothermal Therapy in an Orthotopic Colorectal Tumor Model

J A Damasco, T Y Ohulchanskyy, S Mahajan, G Chen, A Singh, H L Kutscher, H Huang, S G Turowski, J A Spernyak, A K Singh, J F Lovell, M Seshadri, P N Prasad – Excretable, ultrasmall hexagonal NaGdF4:Yb50% nanoparticles for bimodal imaging and radiosensitization

B Pfeifer, C Jones, J Lovell – Pneumococcal vaccine formulations

H I Kilian, A J Pradhan, D Jahagirdar, J Ortega, G E Atilla-Gokcumen, J F Lovell – Light-Triggered Release of Large Biomacromolecules from Porphyrin-Phospholipid Liposomes

C D Bohannon, Z Ende, W Cao, W P Mboko, P Ranjan, A Kumar, M Mishina, S Amoah, S Gangappa, S K Mittal, J F Lovell, A García‐Sastre, B A Pfeifer, B A Davidson, P Knight, S Sambhara – Influenza Virus Infects and Depletes Activated Adaptive Immune Responders

Y Gao, SC Yang, MH Zhu, XD Zhu, X Luan, XL Liu, X Lai, Y Yuan, Q Lu, P Sun, J F Lovell, HZ Chen, C Fang – Metal Phenolic Network-Integrated Multistage Nanosystem for Enhanced Drug Delivery to Solid Tumors

M T Mabrouk, H Zhang, A A Zidan, H I Kilian, WC Huang, D Jahagirdar, J Ortega, J Xia, J F Lovell – Cross-linked Histone as a Nanocarrier for Gut Delivery of Hydrophobic Cargos

Z R Sia, Xn He, A Zhang, J C Ang, S Shao, A Seffouh, WC Huang, M R D’Agostino, A Teimouri Dereshgi, S Suryaprakash, J Ortega, H Andersen, M S Miller, B A Davidson, J F Lovell – A liposome-displayed hemagglutinin vaccine platform protects mice and ferrets from heterologous influenza virus challenge

L Lu, Y Sun, C Wan, Y Hu, PC Lo, JF Lovell, K Yang, H Jin – Role of intravital imaging in nanomedicine-assisted anti-cancer therapy

G Liu, Z Jiang, JF Lovell, L Zhang, Y Zhang – Design of a Thiol-Responsive, Traceless Prodrug with Rapid Self-Immolation for Cancer Chemotherapy

N Anandakrishnan, H Ye, Z Guo, Z Chen, K I Mentkowski, J K Lang, N Rajabian, S T Andreadis, Z Ma, J A Spernyak, J F Lovell, D Wang, J Xia, C Zhou, R Zhao – Fast Stereolithography Printing of Large-Scale Biocompatible Hydrogel Models

XL Liu, X Dong, SC Yang, X Lai, HJ Liu, Y Gao, HY Feng, MH Zhu, Y Yuan, Q Lu, J F Lovell, HZ Chen, C Fang – Targeted Cancer Chemophototherapy: Biomimetic Liposomal Nanoplatinum for Targeted Cancer Chemophototherapy (Adv. Sci. 8/2021)

J Zhou, C Wan, J Cheng, H Huang, JF Lovell, H Jin – Delivery Strategies for Melittin-Based Cancer Therapy

XL Liu, X Dong, SC Yang, X Lai, HJ Liu, Y Gao, HY Feng, MH Zhu, Y Yuan, Q Lu, J F Lovell, HZ Chen, C Fang – Biomimetic Liposomal Nanoplatinum for Targeted Cancer Chemophototherapy

D Wang, H Zhang, T Vu, Y Zhan, A Malhotra, P Wang, U Chitgupi, A Rai, S Zhang, L Wang, J D Huizinga, J F Lovell, J Xia – Trans-illumination intestine projection imaging of intestinal motility in mice

X He, S Zhou, B Quinn, D Jahagirdar, J Ortega, SI Abrams, JF Lovell – HPV-Associated Tumor Eradication by Vaccination with Synthetic Short Peptides and Particle-Forming Liposomes

Y Sun, X Feng, C Wan, JF Lovell, H Jin, J Ding – Role of nanoparticle-mediated immunogenic cell death in cancer immunotherapy

X Yang, H Ren, H Zhang, Gi Liu, Z Jiang, Q Qiu, C Yu, N Murthy, K Zhao, J F Lovell, Y Zhang – Antibiotic Cross-linked Micelles with Reduced Toxicity for Multidrug-Resistant Bacterial Sepsis Treatment

X He, S Zhou, WC Huang, A Seffouh, M T Mabrouk, M T Morgan, J Ortega, S I Abrams, J F Lovell – A Potent Cancer Vaccine Adjuvant System for Particleization of Short, Synthetic CD8+ T Cell Epitopes

J Lovell, D Luo, K Carter, S SHAO, J GENG – Serum-stable compositions and methods for light-triggered release of materials

K Radhakrishnan, T Khamrang, K Sambantham, V Kumar Sali, U Chitgupi, J F Lovell, A A Mohammad, R Venugopal – Identification of cytotoxic copper(II) complexes with phenanthroline and quinoline, quinoxaline or quinazoline-derived mixed ligands

J Federizon, C G T Feugmo, WC Huang, X He, K Miura, A Razi, J Ortega, M Karttunen, J F Lovell – Experimental and Computational Observations of Immunogenic Cobalt Porphyrin Lipid Bilayers: Nanodomain-Enhanced Antigen Association

Y Sun, Y Hu, C Wan, JF Lovell, H Jin, K Yang – Local biomaterial-assisted antitumour immunotherapy for effusions in the pleural and peritoneal cavities caused by malignancies

Sun H., Yan L., Zhang R., Lovell J. F., Wu Y., Cheng C. – A sulfobetaine zwitterionic polymer–drug conjugate for multivalent paclitaxel and gemcitabine co-delivery

Kumar S., Jiang D., Sun B., Seeley K.V., Engle J.W., Sia Z., He X., Neelamegham S., Cai W., Lovell J.F. – Labeling of Erythrocytes by Porphyrin-Phospholipid

2020

M Li, N Nyayapathi, HI Kilian, J Xia, JF Lovell, J Yao – Sound Out the Deep Colors: Photoacoustic Molecular Imaging at New Depths

WC Huang, S Zhou, X He, K Chiem, M T Mabrouk, R H Nissly, I M Bird, M Strauss, S Sambhara, J Ortega, E A Wohlfert, L Martinez‐Sobrido, S V Kuchipudi, B A Davidson, J F Lovell – Vaccines: SARS-CoV-2 RBD Neutralizing Antibody Induction is Enhanced by Particulate Vaccination (Adv. Mater. 50/2020)

S Neelamegham, Q Yang, T A Hughes, A Kelkar, X Yu, K Cheng, S J Park, WC Huang, J F Lovell – Inhibition of SARS-CoV-2 viral entry upon blocking N- and O-glycan elaboration

WC Huang, S Zhou, X He, K Chiem, M T Mabrouk, R H Nissly, I M Bird, M Strauss, S Sambhara, J Ortega, E A Wohlfert, L Martinez‐Sobrido, S V Kuchipudi, B A Davidson, J F Lovell – SARS-CoV-2 RBD Neutralizing Antibody Induction is Enhanced by Particulate Vaccination

JF Lovell – Thinking outside the macrocycle: Potential biomedical roles for nanostructured porphyrins and phthalocyanines

B Sun, H Jing, MT Mabrouk, Y Zhang, H Jin, JF Lovell – A surfactant-stripped cabazitaxel micelle formulation optimized with accelerated storage stability

M T Mabrouk, WC Huang, B Deng, N Li-Purcell, A Seffouh, J Ortega, G E Atilla-Gokcumen, C A Long, K Miura, J F Lovell – Lyophilized, antigen-bound liposomes with reduced MPLA and enhanced thermostability

X Li, JF Lovell, J Yoon, X Chen – Clinical development and potential of photothermal and photodynamic therapies for cancer

Q Yang, T A Hughes, A Kelkar, X Yu, K Cheng, S Park, WC Huang, J F Lovell, S Neelamegham – Inhibition of SARS-CoV-2 viral entry upon blocking N- and O-glycan elaboration

N Anandakrishnan, H Ye, Z Guo, Z Chen, K I Mentkowski, J K Lang, N Rajabian, S T Andreadis, Z Ma, J A Spernyak, J F Lovell, D Wang, J Xia, C Zhou, R Zhao – Fast 3D printing of large-scale biocompatible hydrogel models

Q Yang, T A Hughes, A Kelkar, X Yu, K Cheng, S J Park, WC Huang, J F Lovell, S Neelamegham – Inhibition of SARS-CoV-2 viral entry in vitro upon blocking N- and O-glycan elaboration

G Liu, JF Lovell, L Zhang, Y Zhang – Stimulus-Responsive Nanomedicines for Disease Diagnosis and Treatment

WC Huang, B Deng, M T Mabrouk, A Seffouh, J Ortega, C Long, K Miura, Y Wu, J F Lovell – Particle-based, Pfs230 and Pfs25 immunization is effective, but not improved by duplexing at fixed total antigen dose

ZR Sia, MS Miller, JF Lovell – Engineered Nanoparticle Applications for Recombinant Influenza Vaccines

X Dai, L Lu, S Deng, J Meng, C Wan, J Huang, Y Sun, Y Hu, B Wu, G Wu, J F Lovell, H Jin, K Yang – USP7 targeting modulates anti-tumor immune response by reprogramming Tumor-associated Macrophages in Lung Cancer

SM Abozeid, D Asik, GE Sokolow, JF Lovell, AY Nazarenko, JR Morrow – CoII Complexes as Liposomal CEST Agents

S Shao, WC Huang, C Lin, M D Hicar, C C LaBranche, D C Montefiori, J F Lovell – An Engineered Biomimetic MPER Peptide Vaccine Induces Weakly HIV Neutralizing Antibodies in Mice

A Puri, M Viard, P Zakrevsky, S Zampino, A Chen, C Isemann, S Alvi, J Clogston, U Chitgupi, J F Lovell, B A Shapiro – Photoactivation of sulfonated polyplexes enables localized gene silencing by DsiRNA in breast cancer cells

ZJ Chen, SC Yang, XL Liu, Y Gao, X Dong, X Lai, MH Zhu, HY Feng, XD Zhu, Q Lu, M Zhao, HZ Chen, J F Lovell, C Fang – Nanobowl-Supported Liposomes Improve Drug Loading and Delivery

JH Kim, JT Oh, J Lovell, W SONG, DK Koh, CH Kim, MS Jeon, JK Jung – Apparatus and method for combined photoacoustic and ultrasound diagnosis

C Poon, S Ghosh, X He, S Aygun-Sunar, S Lele, JF Lovell, U Sunar – Fluorescence detection sensitivity of chemophototherapy drug assessed by spatial frequency domain imaging endoscope

C Wan, Y Sun, Y Tian, L Lu, X Dai, J Meng, J Huang, Q He, B Wu, Z Zhang, K Jiang, D Hu, G Wu, J F Lovell, H Jin, K Yang – Irradiated tumor cell-derived microparticles mediate tumor eradication via cell killing and immune reprogramming

WC Huang, B Deng, A Seffouh, J Ortega, C A Long, R V Suresh, X He, K Miura, SM Lee, Y Wu, J F Lovell – Antibody response of a particle-inducing, liposome vaccine adjuvant admixed with a Pfs230 fragment

X Dong, LL Mu, XL Liu, H Zhu, SC Yang, X Lai, HJ Liu, HY Feng, Q Lu, BB S Zhou, HZ Chen, GQ Chen, J F Lovell, DL Hong, C Fang – Biomimetic, Hypoxia-Responsive Nanoparticles Overcome Residual Chemoresistant Leukemic Cells with Co-Targeting of Therapy-Induced Bone Marrow Niches

B Sun, U Chitgupi, C Li, J Federizon, C Zhang, D M Ruszaj, A Razi, J Ortega, S Neelamegham, Y Zhang, J F Lovell – Surfactant-Stripped Cabazitaxel Micelles Stabilized by Clotrimazole or Mifepristone

X Yang, JF Lovell, N Murthy, Y Zhang – Organic Fluorescent Probes for Diagnostics and Bio-Imaging

HI Kilian, D Miranda, JF Lovell – Photoactivatable Drug Release Methods from Liposomes

X Dai, J Meng, S Deng, L Zhang, C Wan, L Lu, J Huang, Y Hu, Z Zhang, Y Li, J F Lovell, G Wu, K Yang, H Jin – Targeting CAMKII to reprogram tumor-associated macrophages and inhibit tumor cells for cancer immunotherapy with an injectable hybrid peptide hydrogel

J Federizon, A Frye, WC Huang, T M Hart, X He, C Beltran, A L Marcinkiewicz, I L Mainprize, M KB Wills, YP Lin, J F Lovell – Immunogenicity of the Lyme disease antigen OspA, particleized by cobalt porphyrin-phospholipid liposomes

Q He, Z Zhang, H Liu, Z Tuo, J Zhou, Y Hu, Y Sun, C Wan, Z Xu, J F Lovell, D Hu, K Yang, H Jin – Relieving immunosuppression during long-term anti-angiogenesis therapy using photodynamic therapy and oxygen delivery

H I Kilian, H Kang, N Nyayapathi, T Fukuda, E Adluru, H Zhang, B Quinn, J Xia, H S Choi, J F Lovell – Facile formulation of a long-wavelength cyanine for optical imaging in the second near-infrared window

2019

H Huang, JF Lovell – Advanced Porphyrin Nanomaterials for Biological Applications

H Liu, Y Hu, Y Sun, C Wan, Z Zhang, X Dai, Z Lin, Q He, Z Yang, P Huang, Y Xiong, J Cao, X Chen, Q Chen, J F Lovell, Z Xu, H Jin, K Yang – Co-delivery of Bee Venom Melittin and a Photosensitizer with an Organic–Inorganic Hybrid Nanocarrier for Photodynamic Therapy and Immunotherapy

U Chitgupi, N Nyayapathi, J Kim, D Wang, B Sun, C Li, K Carter, WC Huang, C Kim, J Xia, J F Lovell – Surfactant-Stripped Micelles for NIR-II Photoacoustic Imaging through 12 cm of Breast Tissue and Whole Human Breasts

S Ghosh, KA Carter, JF Lovell – Liposomal formulations of photosensitizers

S Karpagam, R Kartikeyan, P P Nachiyar, M Velusamy, M Kannan, M Krishnan, U Chitgupi, J F Lovell, M A Akbarsha, V Rajendiran – ROS-mediated cell death induced by mixed ligand copper(II) complexes of l-proline and diimine: effect of co-ligand

LR Parisi, S Sowlati-Hashjin, I A Berhane, S L Galster, K A Carter, J F Lovell, S R Chemler, M Karttunen, G E Atilla-Gokcumen – Membrane Disruption by Very Long Chain Fatty Acids during Necroptosis

L Parisi, N Li, S Sowlati-Hashjin, T Nguyen, K Carter, I Berhane, S Chemler, J Lovell, S Cologna, M Karttunen, G Atilla-Gokcumen – Very long chain fatty acids play a functional role during necroptosis

J Lovell – Single-agent liposomal chemophototherapy for rat mammary tumors

J Lovell, S Shuai, G Jumin, WC Huang, SM Lee, CR King – Nanostructures comprising cobalt porphyrin-phospholipid conjugates and polyhistidine-tags

J Federizon, YP Lin, JF Lovell – Antigen Engineering Approaches for Lyme Disease Vaccines

D Luo, K A Carter, E AG Molins, N L Straubinger, J Geng, S Shao, W J Jusko, R M Straubinger, J F Lovell – Pharmacokinetics and pharmacodynamics of liposomal chemophototherapy with short drug-light intervals

KA Carter, D Luo, J Geng, ST Stern, JF Lovell – Blood Interactions, Pharmacokinetics, and Depth-Dependent Ablation of Rat Mammary Tumors with Photoactivatable, Liposomal Doxorubicin

X Yang, JF Lovell, Y Zhang – Ingestible Contrast Agents for Gastrointestinal Imaging

X Dong, HJ Liu, HY Feng, SC Yang, XL Liu, X Lai, Q Lu, J F Lovell, HZ Chen, C Fang – Enhanced Drug Delivery by Nanoscale Integration of a Nitric Oxide Donor To Induce Tumor Collagen Depletion

JF Lovell – Novel and smart photosensitizers from molecule to nanoparticle

S Ghosh, R Qi, KA Carter, G Zhang, BA Pfeifer, JF Lovell – Loading and releasing ciprofloxacin in photoactivatable liposomes

S Shao, V Rajendiran, JF Lovell – Metalloporphyrin nanoparticles: Coordinating diverse theranostic functions

J Lovell – Liposomal optical activation delivery of agents

V Kabanov, S Ghosh, JF Lovell, B Heyne – Singlet oxygen partition between the outer-, inner- and membrane-phases of photo/chemotherapeutic liposomes

D Miranda, C Wan, HI Kilian, MT Mabrouk, Y Zhou, H Jin, JF Lovell – Indocyanine green binds to DOTAP liposomes for enhanced optical properties and tumor photoablation

H Sun, L Yan, M Y Z Chang, K A Carter, R Zhang, L Slyker, J F Lovell, Y Wu, C Cheng – A multifunctional biodegradable brush polymer-drug conjugate for paclitaxel/gemcitabine co-delivery and tumor imaging

D Miranda, H Huang, H Kang, Y Zhan, D Wang, Y Zhou, J Geng, H I Kilian, W Stiles, A Razi, J Ortega, J Xia, H S Choi, J F Lovell – Highly-Soluble Cyanine J-aggregates Entrapped by Liposomes for In Vivo Optical Imaging around 930 nm

2018

D Moukheiber, U Chitgupi, K A Carter, D Luo, B Sun, S Goel, C A Ferreira, J W Engle, D Wang, J Geng, Y Zhang, J Xia, W Cai, J F Lovell – Surfactant-Stripped Pheophytin Micelles for Multimodal Tumor Imaging and Photodynamic Therapy

WC Huang, B Deng, C Lin, K A Carter, J Geng, A Razi, X He, U Chitgupi, J Federizon, B Sun, C A Long, J Ortega, S Dutta, C Richter King, K Miura, SM Lee, Jonathan F Lovell – A malaria vaccine adjuvant based on recombinant antigen binding to liposomes

ZMO Rzayev, U Bunyatova, JF Lovell, W Shen, T Thomay, A Cartwright – Ag-carried CMC/functional copolymer/ODA-Mt wLED-treated NC and their responses to brain cancer cells

J Lovell, R PANDEY, K Carter, S SHAO – Compositions and method for light triggered release of materials from nanovesicles

B Sun, RM Straubinger, JF Lovell – Current taxane formulations and emerging cabazitaxel delivery systems

WC Huang, ZR Sia, JF Lovell – Adjuvant and Antigen Systems for Malaria Transmission-Blocking Vaccines

X Wang, F Yan, X Liu, P Wang, S Shao, Y Sun, Z Sheng, Q Liu, J F Lovell, H Zheng – Enhanced drug delivery using sonoactivatable liposomes with membrane-embedded porphyrins

X He, SI Abrams, JF Lovell – Peptide Delivery Systems for Cancer Vaccines

H Sun, L Yan, KA Carter, J Zhang, JS Caserto, JF Lovell, Y Wu, C Cheng – Zwitterionic Cross-Linked Biodegradable Nanocapsules for Cancer Imaging

X Luan, YY Guan, HJ Liu, Q Lu, M Zhao, D Sun, J F Lovell, P Sun, HZ Chen, C Fang – A Tumor Vascular-Targeted Interlocking Trimodal Nanosystem That Induces and Exploits Hypoxia

D Wang, D H Lee, H Huang, T Vu, R S A Lim, N Nyayapathi, U Chitgupi, M Liu, J Geng, J Xia, J F Lovell – Ingestible roasted barley for contrast-enhanced photoacoustic imaging in animal and human subjects

MC Butler, U Chitgupi, J Myers, MD Anger, J Lovell, JM Sullivan – Novel Approach to treat Wet Age-Related Macular Degeneration (wAMD) and other Retinal Vascular Diseases

HJ Liu, X Luan, HY Feng, X Dong, SC Yang, ZJ Chen, QY Cai, Q Lu, Y Zhang, P Sun, M Zhao, HZ Chen, J F Lovell, C Fang – Integrated Combination Treatment Using a “Smart” Chemotherapy and MicroRNA Delivery System Improves Outcomes in an Orthotopic Colorectal Cancer Model

V Rajendiran, S Ghosh, JF Lovell – Porphyrin and Phthalocyanine Radiolabeling

H Qiu, M Tan, TY Ohulchanskyy, JF Lovell, G Chen – Recent Progress in Upconversion Photodynamic Therapy

D Miranda, N Li, C Li, F Stefanovic, GE Atilla-Gokcumen, JF Lovell – Detection of Sunlight Exposure with Solar-Sensitive Liposomes that Capture and Release Food Dyes

U Chitgupi, JF Lovell – Naphthalocyanines as contrast agents for photoacoustic and multimodal imaging

U Chitgupi, JF Lovell, V Rajendiran – Assessing Photosensitizer Targeting Using Meso-Tetra(Carboxyphenyl) Porphyrin

U Sunar, J Kress, D J Rohrbach, K A Carter, D Luo, C Poon, S Aygun-Sunar, S Shao, S Lele, J F Lovell – A dual-modal, dual-channel, mesoscopic-scale theranostic endoscope for quantitative imaging, monitoring, and light-triggering of chemodrug release from liposomes in vivo

D Luo, KA Carter, J Geng, X He, JF Lovell – Short Drug–Light Intervals Improve Liposomal Chemophototherapy in Mice Bearing MIA PaCa-2 Xenografts

H Jin, C Wan, Z Zou, G Zhao, L Zhang, Y Geng, T Chen, A Huang, F Jiang, JP Feng, J F Lovell, J Chen, G Wu, K Yang – Tumor Ablation and Therapeutic Immunity Induction by an Injectable Peptide Hydrogel

U Chitgupi, S Shao, KA Carter, WC Huang, JF Lovell – Multicolor Liposome Mixtures for Selective and Selectable Cargo Release

M Macháček, K A Carter, F Kostelanský, D Miranda, A Seffouh, J Ortega, T Šimůnek, P Zimčík, J F Lovell – Binding of an amphiphilic phthalocyanine to pre-formed liposomes confers light-triggered cargo release

2017

D Luo, S Goel, HJ Liu, K A Carter, D Jiang, J Geng, C J Kutyreff, J W Engle, WC Huang, S Shao, C Fang, W Cai, J F Lovell – Intrabilayer 64Cu Labeling of Photoactivatable, Doxorubicin-Loaded Stealth Liposomes

J Kress, D J Rohrbach, K A Carter, D Luo, C Poon, S Aygun-Sunar, S Shao, S Lele, J F Lovell, U Sunar – A dual-channel endoscope for quantitative imaging, monitoring, and triggering of doxorubicin release from liposomes in living mice

D Luo, J Geng, N Li, KA Carter, S Shao, GE Atilla-Gokcumen, JF Lovell – Vessel-Targeted Chemophototherapy with Cationic Porphyrin-Phospholipid Liposomes Free

J Lovell, Y ZHANG, C Kim, M JEON – Surfactant-stripped micelle compositions with high cargo to surfactant ratio

D Miranda, K Carter, D Luo, S Shao, J Geng, C Li, U Chitgupi, S G Turowski, N Li, G E Atilla‐Gokcumen, J A Spernyak, J F Lovell – Multifunctional Liposomes for Image-Guided Intratumoral Chemo-Phototherapy

SL Wang, JF Lovell – Engineering Porphyrin-Phospholipid Nanostructures for Medical Imaging and Therapy

Y Wang, D Wang, Y Zhang, J Geng, R Hubbell, JF Lovell, J Xia – Slit-enabled linear-array photoacoustic tomography with near isotropic spatial resolution in three dimensions

D Wang, Y Wang, Y Zhou, JF Lovell, J Xia – Three-dimensional photoacoustic tomography through coherent-weighted focal-line-based image reconstruction

D Wang, Y Zhou, Y Zhang, J Geng, Y Wang, Y Zhang, T R Cook, J F Lovell, J Xia – Deep-tissue photoacoustic imaging at 1064 nm using a contrast agent based on phosphorus phthalocyanine formulation

U Chitgupi, Y Li, M Chen, S Shao, M Beitelshees, M J Tan, S Neelamegham, B A Pfeifer, C Jones, J F Lovell – Bimodal Targeting Using Sulfonated, Mannosylated PEI for Combined Gene Delivery and Photodynamic Therapy

H Huang, S Chauhan, J Geng, Y Qin, DF Watson, JF Lovell – Implantable Tin Porphyrin-PEG Hydrogels with pH-Responsive Fluorescence

W Song, Y Zhou, JF Lovell – Theranostic applications of photodynamic molecular beacons

Y Zhang, H Hong, B Sun, K Carter, Y Qin, W Wei, D Wang, M Jeon, J Geng, R J Nickles, G Chen, P N Prasad, C Kim, J Xia, W Cai, J F Lovell – Surfactant-stripped naphthalocyanines for multimodal tumor theranostics with upconversion guidance cream

U Chitgupi, Y Qin, JF Lovell – Targeted Nanomaterials for Phototherapy

H Huang, JF Lovell – Advanced Functional Nanomaterials for Theranostics

Y Zhang, JF Lovell – Recent applications of phthalocyanines and naphthalocyanines for imaging and therapy

D Luo, KA Carter, D Miranda, JF Lovell – Chemophototherapy: An Emerging Treatment Option for Solid Tumors

2016

D Wang, Y Wang, W Wang, D Luo, U Chitgupi, J Geng, Y Zhou, L Wang, J F Lovell, J Xia – Deep tissue photoacoustic computed tomography with a fast and compact laser system

J Lovell – Chemophototherapy with Porphyrin-Phospholipid Liposomes: A Treatment Possibility for Solid Tumors

S Shao, T N Do, A Razi, U Chitgupi, J Geng, R J Alsop, B G Dzikovski, M C Rheinstädter, J Ortega, M Karttunen, J A Spernyak, J F Lovell – Design of Hydrated Porphyrin-phospholipid Bilayers with Enhanced Magnetic Resonance Contrast

J Kim, S Park, Y Jung, S Chang, J Park, Y Zhang, JF Lovell, C Kim – Programmable Real-time Clinical Photoacoustic and Ultrasound Imaging System

Y Zhang, D Wang, S Goel, B Sun, U Chitgupi, J Geng, H Sun, T E Barnhart, W Cai, J Xia, J F Lovell – Surfactant-stripped Frozen Pheophytin Micelles for Multimodal Gut Imaging

KA Carter, D Luo, A Razi, J Geng, S Shao, J Ortega, JF Lovell – Sphingomyelin Liposomes Containing Porphyrin-phospholipid for Irinotecan Chemophototherapy

D Miranda, JF Lovell – Mechanisms of light-induced liposome permeabilization

H Huang, D Wang, Y Zhang, Y Zhou, J Geng, U Chitgupi, T R Cook, J Xia, J F Lovell – Axial PEGylation of Tin Octabutoxy Naphthalocyanine Extends Blood Circulation for Photoacoustic Vascular Imaging

X Luan, YY Guan, J F Lovell, M Zhao, Q Lu, YR Liu, HJ Liu, YG Gao, X Dong, SC Yang, L Zheng, P Sun, C Fang, HZ Chen – Tumor priming using metronomic chemotherapy with neovasculature-targeted, nanoparticulate paclitaxel

Y Li, A Hill, M Beitelshees, S Shao, J F Lovell, B A Davidson, P R Knight III, A P Hakansson, B A Pfeifer, C H Jones – Directed vaccination against pneumococcal disease

D Luo, N Li, K A Carter, C Lin, J Geng, S Shao, WC Huang, Y Qin, G E Atilla‐Gokcumen, J F Lovell – Rapid Light-Triggered Drug Release in Liposomes Containing Small Amounts of Unsaturated and Porphyrin–Phospholipids

Y Zhang, W Song, J Geng, U Chitgupi, H Unsal, J Federizon, J Rzayev, D K Sukumaran, P Alexandridis, J F Lovell – Therapeutic surfactant-stripped frozen micelles

R Hernandez, H Huang, J Geng, R Nickles, J Lovell, W Cai – Multimodality imaging of kidney function with a renal clearable porphyrin-PEG polymer

J Kim, S Park, Y Jung, Y Zhang, JF Lovell, C Kim – In Vivo Volumetric Photoacoustic Images of Gastrointestinal Tracts in Rats using Clinical Photoacoustic/Ultrasound Imaging System

U Sunar, J Kress, D J Rohrbach, K A Carter, D Luo, S Shao, S Lele, J F Lovell – Light-triggered doxorubicin release quantified by spatial frequency domain imaging and diffuse optical spectroscopy

D Wang, Y Wang, Y Zhou, JF Lovell, J Xia – Coherent-weighted three-dimensional image reconstruction in linear-array-based photoacoustic tomography

J Kim, S Park, Y Jung, Y Zhang, JF Lovell, C Kim – Clinical real-time photoacoustic/ultrasound imaging system at POSTECH

Y Zhou, D Wang, Y Zhang, U Chitgupi, J Geng, Y Wang, Y Zhang, T R Cook, J Xia, J F Lovell – A Phosphorus Phthalocyanine Formulation with Intense Absorbance at 1000 nm for Deep Optical Imaging

KA Carter, S Wang, J Geng, D Luo, S Shao, JF Lovell – Metal Chelation Modulates Phototherapeutic Properties of Mitoxantrone-Loaded Porphyrin–Phospholipid Liposomes

H Huang, R Hernandez, J Geng, H Sun, W Song, F Chen, S A Graves, R J Nickles, C Cheng, W Cai, J F Lovell – A porphyrin-PEG polymer with rapid renal clearance

D Luo, K A Carter, A Razi, J Geng, S Shao, D Giraldo, U Sunar, J Ortega, J F Lovell – Doxorubicin encapsulated in stealth liposomes conferred with light-triggered drug release

D Luo, KA Carter, A Razi, J Geng, S Shao, C Lin, J Ortega, JF Lovell – Porphyrin-phospholipid liposomes with tunable leakiness

2015

D Luo, KA Carter, A Razi, J Geng, S Shao, C Lin, J Ortega, JF Lovell – Porphyrin-phospholipid liposomes with tunable leakiness

Y Zhang, JF Lovell – Reversible Micro- and Nano- Phase Programming of Anthraquinone Thermochromism Using Blended Block Copolymers

C Lee, J Kim, Y Zhang, M Jeon, C Liu, L Song, JF Lovell, C Kim – Dual-color photoacoustic lymph node imaging using nanoformulated naphthalocyanines

J Rieffel, U Chitgupi, JF Lovell – Recent Advances in Higher-Order, Multimodal, Biomedical Imaging Agents

J Kress, D J Rohrbach, K A Carter, D Luo, S Shao, S Lele, J F Lovell, U Sunar – Quantitative imaging of light-triggered doxorubicin release

U Chitgupi, Y Zhang, C Y Lo, S Shao, W Song, J Geng, S Neelamegham, J F Lovell – Sulfonated Polyethylenimine for Photosensitizer Conjugation and Targeting

G Zheng, JF Lovell – Porphyrin nanovesicles

J Xia, C Kim, J F. Lovell – Opportunities for Photoacoustic-Guided Drug Delivery

F Chen, J Rieffel, G Chen, R Nickles, C Kim, J Lovell, W Cai – Hexamodal imaging in vivo with nanoparticles

S Shao, J Geng, H Ah Yi, S Gogia, S Neelamegham, A Jacobs, JF Lovell – Functionalization of cobalt porphyrin–phospholipid bilayers with his-tagged ligands and antigens

G Zheng, J Lovell – Method for the synthesis of porphyrin-phospholipid conjugates

H Huang, W Song, J Rieffel, JF Lovell – Emerging applications of porphyrins in photomedicine

JH Lee, S Shao, KT Cheng, JF Lovell, CH Paik – 99mTc-labeled porphyrin–lipid nanovesicles

D Luo, KA Carter, JF Lovell – Nanomedical engineering: shaping future nanomedicines

JH Kim, JT Oh, J Lovell, W SONG, DK Koh, CH Kim, MS Jeon, JK Jung – Contrast agent for combined photoacoustic and ultrasound imaging

J Rieffel, F Chen, J Kim, G Chen, W Shao, S Shao, U Chitgupi, R Hernandez, S A Graves, R J Nickles, P N Prasad, C Kim, W Cai, J F Lovell – Hexamodal Imaging with Porphyrin-Phospholipid-Coated Upconversion Nanoparticles

JF Lovell – Functionalization of cobalt porphyrin–phospholipid bilayers with his-tagged ligands and antigens

2014

G Zheng, J Lovell, E Huynh – Giant Porphyrin-Phospholipid Vesicles

G Zheng, J Lovell, E Huynh – Porphyrin Microbubbles

J A Damasco, G Chen, W Shao, H Ågren, H Huang, W Song, J F Lovell, P N Prasad – Size-Tunable and Monodisperse Tm3+/Gd3+-Doped Hexagonal NaYbF4 Nanoparticles with Engineered Efficient Near Infrared-to-Near Infrared Upconversion for In Vivo Imaging

Y Zhang, M Jeon, L J Rich, H Hong, J Geng, Y Zhang, S Shi, T E Barnhart, P Alexandridis, J D Huizinga, M Seshadri, W Cai, C Kim, J F Lovell – Non-invasive multimodal functional imaging of the intestine with frozen micellar naphthalocyanines

H Huang, W Song, G Chen, J M Reynard, T Y Ohulchanskyy, P N Prasad, F V Bright, JF Lovell – Pd-Porphyrin-Cross-Linked Implantable Hydrogels with Oxygen-Responsive Phosphorescence

KA Carter, S Shao, M I Hoopes, D Luo, B Ahsan, V M Grigoryants, W Song, H Huang, G Zhang, R K Pandey, J Geng, B A Pfeifer, C P Scholes, J Ortega, M Karttunen, J F Lovell – Porphyrin–phospholipid liposomes permeabilized by near-infrared light

M Jeon, W Song, J Kim, J Kim, J Oh, J Lovell, C Kim – Methylene blue microbubbles (MB2) as a dual modal contrast agent for photoacoustic and ultrasound imaging

E Huynh, JF Lovell, R Fobel, G Zheng – Optically Controlled Pore Formation in Self-Sealing Giant Porphyrin Vesicles

K W Yip, Z Zhang, N Sakemura-Nakatsugawa, JW Huang, N Mai Vu, YK Chiang, CL Lin, J YY Kwan, S Yue, Y Jitkova, T To, P Zahedi, E F Pai, A D Schimmer, J F Lovell, J L Sessler, FF Liu – A Porphodimethene Chemical Inhibitor of Uroporphyrinogen Decarboxylase

T E Barnhart, P Alexandridis, J D Huizinga, M Seshadri, W Cai, C Kim, J F Lovell – Non-invasive multimodal functional imaging of the intestine with frozen micellar naphthalocyaninese

K Lou, JF Lovell – A quenched binuclear ruthenium(ii) dimer activated by another photosensitizer

M Jeon, W Song, E Huynh, J Kim, J Kim, B L Helfield, B YC Leung, D E Goertz, G Zheng, J Oh, J F Lovell, C Kim – Methylene blue microbubbles as a model dual-modality contrast agent for ultrasound and activatable photoacoustic imaging

2013

KK Ng, JF Lovell, A Vedadi, T Hajian, G Zheng – Self-Assembled Porphyrin Nanodiscs with Structure-Dependent Activation for Phototherapy and Photodiagnostic Applications

CS Jin, JF Lovell, J Chen, G Zheng – Ablation of Hypoxic Tumors with Dose-Equivalent Photothermal, but Not Photodynamic, Therapy Using a Nanostructured Porphyrin Assembly

CS Jin, JF Lovell, G Zheng – One Minute, Sub-One-Watt Photothermal Tumor Ablation Using Porphysomes, Intrinsic Multifunctional Nanovesicles

DH Yu, FQ Ban, M Zhao, Q Lu, J F Lovell, F Bai, C Wang, YY Guan, X Luan, YR Liu, C Fang, HZ Chen – The use of nanoparticulate delivery systems in metronomic chemotherapy

2012

Y Zhang, JF Lovell – Porphyrins as Theranostic Agents from Prehistoric to Modern Times

E Huynh, J F Lovell, B L Helfield, M Jeon, C Kim, D E Goertz, B C Wilson, G Zheng – Porphyrin Shell Microbubbles with Intrinsic Ultrasound and Photoacoustic Properties

JF Lovell, CS Jin, E Huynh, TD MacDonald, W Cao, G Zheng – Enzymatic Regioselection for the Synthesis and Biodegradation of Porphysome Nanovesicles

J F Lovell, C S Jin, E Huynh, T D MacDonald, W Cao, G Zheng – Enzymatic Regioselection for the Synthesis and Biodegradation of Porphysome Nanovesicles

H Jin, J Chen, J F Lovell, S Shang, G Sheng – Synthesis and Development of Lipoprotein-Based Nanocarriers for Light-Activated Theranostics

H Jin, J F Lovell, J Chen, Q Lin, L Ding, K K Ng, R K Pandey, M Manoharan, Z Zhang, G Zheng – Mechanistic Insights into LDL Nanoparticle-Mediated siRNA Delivery

2011

JF Lovell, MW Chan, Q Qi, J Chen, G Zheng – Porphyrin FRET Acceptors for Apoptosis Induction and Monitoring

J F Lovell, A Roxin, K K Ng, Q Qi, J D McMullen, R S DaCosta, G Zheng – Porphyrin-Cross-Linked Hydrogel for Fluorescence-Guided Monitoring and Surgical Resection

KK Ng, JF Lovell, G Zheng – Lipoprotein-Inspired Nanoparticles for Cancer Theranostics

J F Lovell, C S Jin, E Huynh, H Jin, C Kim, J L Rubinstein, W CW Chan, W Cao, L V Wang, G Zheng – Porphysome nanovesicles generated by porphyrin bilayers for use as multimodal biophotonic contrast agents

H Jin, JF Lovell, J Chen, K Ng, W Cao, L Ding, Z Zhang, G Zheng – Cytosolic delivery of LDL nanoparticle cargo using photochemical internalization

M Yang, H Jin, J Chen, L Ding, K K Ng, Q Lin, J F Lovell, Z Zhang, G Zheng – Efficient Cytosolic Delivery of siRNA Using HDL-Mimicking Nanoparticles

2010

H Jin, JF Lovell, J Chen, K Ng, W Cao, L Ding, Z Zhang, G Zheng – Investigating the specific uptake of EGF-conjugated nanoparticles in lung cancer cells using fluorescence imaging

JF Lovell, H Jin, KK Ng, G Zheng – Programmed Nanoparticle Aggregation Using Molecular Beacons

JF Lovell, J Chen, E Huynh, MT Jarvi, BC Wilson, G Zheng – Facile Synthesis of Advanced Photodynamic Molecular Beacon Architectures

JF Lovell, TWB Liu, J Chen, G Zheng – Activatable Photosensitizers for Imaging and Therapy

Z Zhang, J Chen, L Ding, H Jin, JF Lovell, I R Corbin, W Cao, PC Lo, M Yang, MS Tsao, QLuo, G Zheng – HDL-Mimicking Peptide–Lipid Nanoparticles with Improved Tumor Targeting

2009

Z Zhang, W Cao, H Jin, J F Lovell, M Yang, L Ding, J Chen, I Corbin, Q Luo, G Zheng – Biomimetic Nanocarrier for Direct Cytosolic Drug Delivery

J F Lovell, J Chen, M T Jarvi, WG Cao, A D Allen, Y Liu, T T Tidwell, B C Wilson, G Zheng – FRET Quenching of Photosensitizer Singlet Oxygen Generation

2008

J Chen, JF Lovell, PC Lo, K Stefflova, M Niedre, BC Wilson, G Zheng – A tumor mRNA-triggered photodynamic molecular beacon based on oligonucleotide hairpin control of singlet oxygen production

JF Lovell, G Zheng – ACTIVATABLE SMART PROBES FOR MOLECULAR OPTICAL IMAGING AND THERAPY

J F Lovell, L P Billen, S Bindner, A Shamas-Din, C Fradin, B Leber, D W Andrews – Membrane Binding by tBid Initiates an Ordered Series of Events Culminating in Membrane Permeabilization by Bax

LP Billen, CL Kokoski, JF Lovell, B Leber, DW Andrews – Bcl-XL Inhibits Membrane Permeabilization by Competing with Bax