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POPESCU LABORATORY

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BMS 503
kinetic modeling
signal transduction
allosteric modulation
frequency detection
synaptic physiology

MOLECULAR PHYSIOLOGY OF NMDA RECEPTORS

To understand molecular mechanisms for fast information transfer and integration at excitatory synapses we focus our research on
  NMDA RECEPTORS.
 We seek to define their activation pathway, modulatory mechanisms and structure-function relationships to better understand the roles played by these proteins in the brain. NMDA receptors are involved in synaptic development, plasticity, memory, and learning and in several neuropathologies including stroke, neurodegeneration, chronic pain, addiction, schizophrenia and epilepsy.

research opportunities

 

"Without research to guide us all answers are mere opinions."
Albert Einstein

   
Department of Biochemistry, 140 Farber Hall, 3435 Main Street, Buffalo NY 14214
Phone: 716-829-3807, Fax: 716-829-2725, E-mail: popescu@buffalo.edu