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Recent Publications
Functional Mapping
Polyploid Mapping
Linkage Disequilibrium Mapping
Mapping in Outcrossing Species
Seed Development Mapping
Sequencing Complex Traits with HapMap
Molecular Map Construction
Functional Mapping
Ma,
C.-X., R. L. Wu and G. Casella, 2004 FunMap: Functional mapping of complex
traits. Bioinformatics 20: 1808-1811.
Ma, C.-X., M. Lin, G. Casella, R. C. Littell, T. M. Yin and R.
L. Wu, 2004 A statistical model for mapping growth trajectories using dominant
markers. Theoretical and Applied Genetics
108: 699-705.
Zhao, W., C.-X. Ma, J. M. Cheverud and R. L. Wu, 2004 A unifying
statistical model for QTL mapping of genotype-sex interaction for developmental
trajectories. Physiological Genomics 19: 218-227.
Zhao,
W., R. L. Wu, C.-X. Ma and G. Casella, 2004 A fast algorithm for functional
mapping of complex traits. Genetics 167:
2133-2137.
Zhao,
W., J. Zhu, M. Gallo-Meagher and R. L. Wu,
2004 A unified statistical model for functional mapping of genotype-environment
interactions for ontogenetic development. Genetics 169: 000-000.
Liu, T., W. Zhao, L. L. Tian and R. L. Wu, 2004 An algorithm
for molecular dissection of tumor progression. Journal of Mathematical Biology (in press).
Wu, R. L., Z. H. Wang, W. Zhao and J. M. Cheverud, 2004 A
mechanistic model for genetic machinery of ontogenetic growth. Genetics (in press).
Lin, M., W. Zhao and R. L. Wu, 2004 A genetic model for
power curves in bird flight. Mathematical
Medicine and Biology (accepted).
Wang,
Z. H., and R. L. Wu, 2004 A statistical model for high-resolution mapping of
quantitative trait loci determining human HIV-1 dynamics. Statistics in Medicine 23: 3033-3051.
Gong, Y., Z. H. Wang, T. Liu, W. Zhao, Y. Zhu and R. L. Wu,
2004 A statistical model for high-resolution mapping of quantitative trait loci
affecting pharmacodynamic processes. The Pharmacogenomics
Journal 4: 315-321.
Wu, R. L., C.-X. Ma, M. Lin, Z. H. Wang and G. Casella, 2004 Functional mapping
of growth QTL using a transform-both-sides logistic model. Biometrics 60: 729-738.
Wu, R. L., C.-X. Ma, M. Lin and G. Casella, 2004 A general
framework for analyzing the genetic architecture of developmental
characteristics. Genetics 166: 1541-1551.
Wu, R. L., C.-X. Ma, Y.-X. Lou and G. Casella, 2003
Molecular dissection of allometry, ontogeny and plasticity: A genomic view of
developmental biology. BioScience 53: 1041-1047.
Ma, C. X., G. Casella, R. C. Littell, K. A. I. Khuri and R.
L. Wu, 2003 Exponential mapping of quantitative traits governing allometric relationships
in organisms. Journal of Mathematical Biology 47: 313-324.
Wu, R. L., C.-X. Ma, W. Zhao and G. Casella, 2003 Functional mapping of
quantitative trait loci underlying growth rates: A parametric model. Physiological
Genomics 14: 241-249.
Wu, R. L., C. X. Ma, M. C. K. Yang, M. Chang, U. Santra, S. S. Wu, M. Huang, M.
Wang and G. Casella, 2003 Quantitative trait loci for growth in Populus. Genetical
Research 81: 51-64. [Abstract]
[Full
Text]
Wu, R. L., C. X. Ma, M. Chang, R. C. Littell, S. S. Wu, M.
Huang, M. Wang and G. Casella, 2002 A logistic mixture model for detecting
major genes governing growth trajectories. Genetical Research 79:235-245.
[Abstract]
[Full
Text]
Wu, R. L., C. X. Ma, R. C. Littell and G. Casella, 2002 A
statistical model for the genetic origin of allometric scaling laws in biology.
Journal of Theoretical Biology 217: 275-287. [Abstract]
[Full
Text]
Ma, C. X., G. Casella, and R. L. Wu, 2002 Functional mapping
of quantitative trait loci underlying the character process: A theoretical
framework. Genetics 161: 1751-1762. [Abstract]
[Full Text]
Wu, R. L., C.-X. Ma, J. Zhu and G. Casella, 2002 Mapping
epigenetic quantitative trait loci (QTL) altering a developmental trajectory. Genome
45: 28-33. [Abstract]
[Full
Text]
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Polyploid Mapping
Wu, R. L., C.-X. Ma and G.
Casella, 2004 A bivalent polyploid model for mapping quantitative trait loci in
outcrossing tetraploids. Genetics 166: 581-595.
Wu, R. L., C. X. Ma and G. Casella, 2004 A mixed polyploid model for linkage
analysis in tetraploids. Journal of Computational Biology 11: 562-580.
Wu, R. L., C.-X. Ma and G. Casella, 2002 A bivalent polyploid model for linkage
analysis in outcrossing tetraploid species. Theoretical Population Biology
62: 129–151. [Abstract]
[Full
Text]
Ma, C.-X., G. Casella, T. C. Osborn and R. L. Wu, 2002 A unified framework for
mapping quantitative trait loci in bivalent tetraploids using single-dose
restriction fragments: A case study from alfalfa. Genome Research 12:
1974-1981. [Abstract]
[Full Text]
Wu, S. S., R. L. Wu, C. X. Ma, Z.-B. Zeng, M. Yang and G. Casella, 2001 A
multivalent pairing model of linkage analysis in autotetraploids. Genetics 159:
1339-1350 (the first two authors contribute equally to this work). [Abstract]
[Full Text]
Wu, R. L., M. Gallo-Meagher, R. C. Littell and Z.-B. Zeng, 2001 A general
polyploid model for analyzing gene segregation in outcrossing autotetraploid
species. Genetics 159: 869-882. [Abstract]
[Full Text]
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Linkage Disequilibrium Mapping
Lou, X.-Y., G. Casella, R. J. Todhunter, M. C. K. Yang and
R. L. Wu, 2004 A general statistical
framework for unifying interval and linkage disequilibrium mapping: Towards
high-resolution mapping of quantitative traits. Journal of American Statistical Association 99: 000-000.
Lou, X.-Y., R. J. Todhunter, M. Lin, Q. Lu, T. Liu, Z. H.
Wang, S. Bliss, G. Casella, A. C. Acland, G. Lust and R. L. Wu, 2003 The extent and distribution of
linkage disequilibrium in canine. Mammalian
Genome 14: 555-564.
Lou, X.-Y., G. Casella, R. C. Littell, M. K. C. Yang and R. L. Wu, 2003 A
haplotype-based algorithm for multilocus linkage disequilibrium mapping of
quantitative trait loci with epistasis in natural populations. Genetics 163:
1533-1548. [Abstract]
[Full Text]
Wu, R. L., C.-X. Ma and G. Casella, 2002 Joint linkage and linkage
disequilibrium mapping of quantitative trait loci in natural populations. Genetics
160: 779-792. [Abstract]
[Full Text]
Wu, R. L., and Z-B. Zeng, 2001 Joint linkage and linkage disequilibrium
mapping in natural populations. Genetics 157: 899-909. [Abstract]
[Full Text]
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Mapping in Outcrossing Species
Lu, Q., Y. H. Cui and R.
L. Wu, 2004 A multilocus likelihood approach to joint modeling of linkage,
parental diplotype and gene order in a full-sib family. BMC Genetics 5: 20 (http://www.biomedcentral.com/content/pdf/1471-2156-5-20.pdf).
Lin, M., X.-Y. Lou, M. Chang and R. L. Wu, 2003 A general
statistical framework for mapping quantitative trait loci in non-model systems:
Issue for characterizing linkage phases. Genetics 165: 901-913.
Wu, R. L., C. X. Ma, S. S. Wu and Z-B. Zeng, 2002 Linkage mapping of
sex-specific differences. Genetical Research 79: 85-96. [Abstract]
[Full
Text]
Wu, R. L., C.-X. Ma, I. Painter and Z.-B. Zeng, 2002 Simultaneous maximum
likelihood estimation of linkage and linkage phases in outcrossing species. Theoretical
Population Biology 61: 349-363. [Abstract]
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Text]
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Seed Development Mapping
Cui, Y. H., G. Casella and R.
L. Wu, 2004 Mapping quantitative trait locus interactions from the maternal and
offspring genomes. Genetics 167: 1017-1026.
Wu, R. L., X.-Y. Lou, C.-X. Ma,
X. L. Wang, B. A. Larkins and G. Casella, 2002 An improved genetic model
generates high-resolution mapping of QTL for protein quality in maize
endosperm. Proceedings of the National Academy of Sciences of the United
States of America 99: 11281–11286. [Abstract]
[Full
Text]
Wu, R. L., C.-X. Ma, M. Gallo-Meagher, R. C. Littell and G. Casella, 2002
Statistical methods for dissecting triploid endosperm traits using molecular
markers: An autogamous model. Genetics 162: 875-892. [Abstract]
[Full Text]
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Sequencing Complex Traits with HapMap
Liu, T., J. A. Johnson, G. Casella and R. L. Wu, 2004 Sequencing
complex diseases with HapMap. Genetics
168: 000-000.
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Molecular Map Construction
Zhang, B., T. M. Yin, Q. Zhuge, Z. M. Han, M. X. Wang, R. L. Wu and M. R.
Huang, 2002 Detection of genes affecting fusiform diseases in poplars using
molecular markers. Hereditas (Beijing) 23: 400-404.
Yin, T. M., X. Y. Zhang, M. R. Huang, M. X. Wang, Q. Zhuge, S. M. Tu, L.-H. Zhu
and R. L. Wu, 2002 The molecular linkage maps of the Populus genome. Genome 45:
541-555. [Abstract]
[Full
Text]
Yin, T. M., M. R. Huang, M. X. Wang, Z.-B. Zeng and R. L. Wu, 2001
Interspecific linkage maps of Populus adenopoda ´ P. alba. Genome 44:
602-609. [Abstract]
[Full
Text]
Zhang, X. Y., D. M. Yin, Q. Zhuge, M. R. Huang, L. H. Zhu, W. X. Zhai, R. L. Wu
and M. X. Wang, 2000 RAPD linkage mapping in a P. deltoides ´ P. euramericana
F1 family. Hereditas (Beijing) 22: 209-213.
Wu, R. L., Y. F. Han, J. J. Hu, L. Li, M. L. Li and Z-B. Zeng, 2000 An
integrated genetic map of Populus based on amplified fragment length
polymorphisms. Theoretical and Applied Genetics 100: 1249-1256.
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