Translational Control of Gene Expression



10/14/2022 - Sarah, Ansuman and Qian travel to Cleveland for RRM. Ansuman gave a talk and Qian presented a poster.

9/18/2022 - New preprint from our collaboration with the Barbi lab on eIF4B dysregulation effects in metastatic breast cancer.

9/12/2022 - Welcome to Ira and Rutuja, two Ph.D. students rotating this fall.

9/10/2022 - Qian gives her first conference talk at the CSHL Meeting on Translational Control on growth, RNA-binding, and other changes affected by phosphorylation of eIF4A that occurs on glucose removal in yeast.

8/20/2022 - Sarah gives a talk at YGM in Los Angeles on Ansuman's recently submitted work.

7/29/2022 - Maria gives her poster at the REU symposium. Maria purified 5 eIF4B variants and ribosomes and performed a bunch of anisotropy experiments in <8 weeks in lab. Thanks for all your hard work this summer!

6/6/2022 - Welcome Adaora and Maria!

6/1/2022 - Congratulations to Austin on finishing his M.S. and Ritika and Sam for finishing their bachelors degrees! The lab celebrated with lunch. Good luck to all of you as you move on!

4/11/2022 - Welcome to Nissa, our new undergraduate lab assistant

4/8/2022 - Congratulations to Sam for accepting a spot in the MIT Biology Ph.D. program! Congratulations to Ritika for acce- ptance at  University  of  Toronto  Molecular  Biology  and  Genetics,  and  for  being selected to graduate with high honors in Biology! We are so proud of both of your accomplishments at UB and can't wait to see what you do in grad school!

12/7/2021 - We decorated for the holidays with a Chemis-tree and Sarah's lemon tree got an upgrade. Stop by the Walker lab desk area to admire the creative work and have some candy...the tree really does look better in person.

12/3/2021 - Our paper on eIF4B influence on translation and phenotype is accepted at Frontiers in Molecular Biosciences.

5/26/2021 - We have a new commentary in JMB highlighting work on aEF1B. Flipping the Switch: An Unexpected Role for aEF1B in Modulating aEF1A Interactions with the Ribosome and tRNA

5/16/2021 - Congrats to Tom on completing his M.S. Good luck at Rochester!

2/9/2021 - A paper from the Ferkey lab is out. Ansuman and Sarah enjoyed helping Zander determine effects of dopamine receptor methylation on interactions with two ligands. Methylation of the D2 dopamine receptor affects binding with the human regulatory proteins Par-4 and Calmodulin.

1/31/2021 - Congrats to Sam for getting into a summer research program at MIT

1/28/2021 - Congrats to Tom on winning 1st place for his poster on eIF4B in breast cancer, his second poster award

December 2020 - The lab welcomes Austin D'Angelo for a rotation looking at yeast eIF4B interactions in complexes

10/25/2020 - Congratulations to Ansuman for being awarded a Mark Diamond Research Fund Grant!

10/23-10/24/2020 - The Walker lab attends the RRM virtually to get a translation fix. Sarah chaired the translational control session, Ansuman gave his first conference talk on eIF4A, and Tom gave his first conference poster on eIF4B.

September 2020 - Welcome back Sam and Karrar! The Walker lab has a number of carefully-considered measures in place to keep lab capacity low and everyone safe. We are glad two of our undergrads are able to return to research for the fall.

March - June 2020 - The lab shuts down due to the COVID-19 pandemic. Ansuman was awarded a travel grant for the ASBMB annual meeting (cancelled), and Peter was invited to present a flash talk. Karrar was awarded the Raszl fellowship for undergraduate research, and he and Amy did online research projects with Sarah for the McNair program over the summer. Great work Karrar! Congratulations also to Leila on completing her M.S. and Qian for passing to candidacy in May! Good luck to Leila in her new position!

2/16/2020 - Sarah had a great visit at the University of Richmond

2/7/2020 - The lab welcomes Tom!

1/23/2020 - Congratulations to Tom for being awarded a poster prize at the departmental symposium!

11/13/2019 - Sarah hosts Sofia Origanti for departmental seminar

10/29/2019 - Our submitted work on eIF4B phenotypic effects is available to read on BioRXIV

10/25/2019 - The lab headed to Cleveland for the RRM and caught up with a lot of Rustbelt area translation groups, including 4/5 of Sarah's dissertation committee!

10/17/2019 - Sarah hosts Ruben Gonzalez for departmental seminar

6/21/2019 - Sarah organized her first conference with Paul Cullen. Thanks to the Walker and Cullen lab members for helping make the NERY (Northeast Regional Yeast) meeting a success! Dalton presented a talk on eIF4B regulation of translation, and Ansuman and Qian gave posters on their work on eIF4A and eIF4B projects.

5/30/2019 - Congratulations to Dalton for winning another first place poster prize, this time at the UB Postdoc symposium!

5/2/2019 - Sarah hosts Angie Hilliker for departmental seminar

4/7/2019 - Sarah gives a talk and chairs the session on Protein Structure and Function at ASBMB in Orlando

3/23/2019 - Congratulations to Dalton, Peter, and Ansuman on the acceptance of a Methods paper

2/11/2019 - Welcome to Leila and Qian!

2/1/2019 - The lab hosts the first Cooke 5 First Friday Happy Hour with yeast-fermented ginger beer and lots of snacks, a nice celebration of a paper submission

1/24/2019 - Congratulations to Rebecca for winning first place rotation poster at the Department symposium for her collaborative work on eIF1A methylation with Mike Yu!

1/22/2019 - Sarah gives the keynote talk for the Genetics, Genomics, Bioinformatics Research Day

1/15/2019 -  Walker lab is moved into newly renovated Biological Sciences floor

11/26/2018 - The lab welcomes Rebecca Wegman and Leila Zabihi for the second rotation and thanks Qian for successfully completing DMS-MaPSeq experiments in the first rotation!

10/26/2018 - Dalton and Ansuman travel to Columbus for the Rustbelt RNA Meeting, where Dalton gave a talk on his ribosome profiling results and Ansuman presented a poster on eIF4A phosphorylation

9/10/2018 - Genetics lab protocol, "CRISPR gene editing in yeast: An experimental protocol for an upper-division undergraduate laboratory course." (on which Ansuman and Sarah are coauthors) is accepted at Biochemistry and Molecular Biology Education journal

9/10/2018 - The lab welcomes Ph.D. students Qian He and Selam Weldegebriel for the first rotation

9/4/2018 - Sarah and Ansuman travel to CSHL for the Translational Control Meeting

8/14/2018 - Good luck to Jessie as she starts graduate school!

8/1/2018 - Congratulations to Jay on receiving his M.S. in Biology. Good luck in your new position!

5/29/2018 - Dalton, Jay, and Peter travel to Berkeley for the RNA Society Meeting

4/19/2018 - Sarah hosts Nick Guydosh for departmental seminar

4/17/2018 - The lab welcomes Qian He for a "pre-rotation"

3/16/2018 - The lab travels to Albany for the RNA Institute Annual Meeting. Dalton is awarded Best Poster Prize!

1/25/2018 - Congratulations to Peter for getting 1st place on his poster at the Departmental Symposium!