Xue Wang

Introduction

Dr. Xue Wang got her B.S. & M.S. degrees from East China Normal University. Her previous research involved drug development and identification of potential targets. She got her Ph. D degree at Roswell Park Cancer Institute. Her research interests include: 1) high-resolution and large-scale expression profiling of pathological proteomics; 2) targeted quantification of regulatory, marker proteins for clinical study.

Publications

1. Shen X, Shen S, Li J, Hu Q, Nie L, Tu C, Wang X, Poulsen DJ, Orsburn BC*, Wang J*, Qu J*. IonStar enables high-precision, low-missing-data proteomics quantification in large biological cohorts. Proc Natl Acad Sci USA. In Press. (2018)

2. Wang X, Niu J, Li J, Shen X, Shen S, Straubinger RM, Qu J*. Temporal Effects of Combined Birinapant and Paclitaxel on Pancreatic Cancer Cells Investigated via Large-Scale, Ion-Current-Based Quantitative Proteomics (IonStar). Mol Cell Proteomics. 17(4):655-671. (2018)

3. Zhang M, An B, Qu Y, Shen S, Fu W, Chen YJ, Wang X, Young R, Canty JM Jr., Balthasar JR, Murphy K, Bhattacharyya D, Josephs J, Ferrari L, Zhou S, Bansal S, Vazvaei F*, Qu J*. Sensitive, High-Throughput, and Robust Trapping-Micro-LC-MS Strategy for the Quantification of Biomarkers and Antibody Biotherapeutics. Anal Chem. 90(3):1870-1880. (2018)

4. Fu W, An B, Wang X, Qu J*. Key considerations for LC-MS analysis of protein biotherapeutics in tissues. Bioanalysis. 9(18):1349-1352. (2017)

5. Shen X, Shen S, Li J, Hu Q, Nie L, Tu C, Wang X, Orsburn B, Wang J, Qu J*. An IonStar experimental strategy for MS1 ion current-based quantification using ultra-high-field Orbitrap: reproducible, in-depth and accurate protein measurement in larger cohorts. J Proteome Res. 16(7):2445-2456. (2017)

6. Tu C, Sheng Q, Li J, Ma D, Shen X, Wang X, Shyr Y, Yi Z, Qu J*. Optimization of Search Engines and Postprocessing Approaches to Maximize Peptide and Protein Identification for High-Resolution Mass Data. J Proteome Res. 14(11):4662-73 (2015)