During the summers of my Sophmore and Junior years at UB, I have been a part of the NSF BioXFEL program.
My projects focused on attempting to extend the principles of non-linear analysis of conformations of single particle data. Established by our group are effective methods for analyzing single particle projection snapshots within a given orientation window. I looked into improving aspects of our methodology using ideas from recently published papers. The nature of this dimensionality reduction I try to explain