Education and Training
Ph. D.,
Nuclear Medicine and Radiobiology, 1997, University of Sherbrooke, Quebec,
Canada.
Master of Engineering, Engineering Physics, 1987, Tsinghua University,
Beijing, P. R. China.
Bachelor of Engineering, Engineering Physics, 1985, Tsinghua University,
Beijing, P. R. China.
Visitor
Fellowship at National Institutes of Health, United States of America,
1997-1999.
Research Interests
Dr. Yao's
research focuses on developing advanced medical imaging systems, such as
single photon emission computed tomography (SPECT) and positron emission
tomography (PET). Both SPECT and PET are based on detection of high energy
(~80 to 650 keV) photons. His recent research projects are about developing
multiple imaging functionalities, for example, SPECT and CT (Computed
Tomography), SPECT and PET, on a single scintillation detector system. Sample
Projects.
Peer Reviewed Publications
1.
Avinash
Srivatsan, Paula Pera, Penny Joshi, Joseph R Missert, Erin C Tracy, Walter
Tabacznski, Rutao Yao, Munawwar
Sajjad, Heinz Baumann, Ravindra K. Pandey "Effect of chirality on cellular
uptake, imaging and photodynamic therapy of photosensitizers derived from
chlorophyll-a," Bioorganic & Medicinal Chemistry, in press.
2.
Y. Jian, R. Yao, T Mulnix, X Jin and R E
Carson, "Applications of the line-of-response probability density function
resolution model in PET list mode reconstruction," Physics in Medicine and
Biology, Vol. 60, pp. 253-278, 2015.
3.
Anurag Gupta,
Shouyan Wang, Aimee Marko, Penny Joshi, Manivannan Ethirajan, Yihui Chen, Rutao Yao, Munawwar Sajjad, Raoul
Kopelman, Ravindra K. Pandey "Polyacrylamide-Based Biocompatible
Nanoplatform Enhances the Tumor Uptake, PET/fluorescence Imaging and
Anticancer Activity of a Chlorophyll Analog," Theranostics, vol. 4,
issue 6, pp. 614-628, 2014.
4.
X. Deng, J.-F.
Beaudoin, J. Cadorette, C. Naaman, R. Lecomte, and R. Yao, "PET imaging based geometrical calibration for a
dual-modality PET/SPECT animal scanner," Physics in Medicine and Biology,
vol. 58, pp. 2011-2025, 2013, IOP Featured
Article.
5.
R. Yao, X. Deng,
J.-F. Beaudoin, T. Ma, J. Cadorette, Z. Cao, and R. Lecomte, "Initial
Evaluation of a Lab-PET/SPECT Dual Modality Animal Imaging System," IEEE
Transactions on Nuclear Science, vol. 60, no. 1, pp. 76-81, 2013.
6.
Y. Xia, R. Yao, X. Deng, Y. Liu, S. Wang, and
T. Ma, "A Hybrid Rotation-Translation Scan Scheme for In Vivo Animal SPECT
Imaging on a Stationary Scanner", Physics in Medicine and Biology, vol. 58,
pp. 965-983, 2013.
7.
R. Yao, R. M.
Ramachandra, N. Mahajan, V. Rathod, N. Gunasekar, A. Panse, T. Ma, Y. Jian,
J. Yan, R. E. Carson, "Assessment of a Three-Dimensional Line-of-Response
Probability Density Function System Matrix for PET," Physics in Medicine and
Biology, vol. 57, pp. 6827-6848, 2012.
8. R. Yao, R. Lecomte, and E. S. Crawford, "micro-PET: what is it
and why do we need it", Journal of Nuclear Medicine Technology, vol. 40, pp.
157-165, September 2012.
9. A. Jain, A. Panse, D. R. Bednarek, R. Yao, and S. Rudin, "Evaluation of the Micro-Angiographic
Fluoroscope as a High Resolution, Single-Photon Counting and Energy
Integrating Imager for Transmission and Emission Imaging", IEEE Transactions
on Nuclear Science, vol. 59, no. 5, pp. 1927-1933, 2012.
10.
M. Sajjad, U.
Riaz, R. Yao, M. M. Abouzeid, D.
A. Erb, R. J. Bernacki, N. D. Chaudhary, J. M. Veith, G. Georg and H. A.
Nabi, "3'-(3-[123, 124I]iodobenzoyl)-3'-debenzoylpaclitaxel as radio-tracers
to study multidrug resistance in vivo", Applied Radiation and Isotopes, vol.
70, pp. 1624-1631, August 2012.
11.
X. Deng, T. Ma,
R. Lecomte, and R. Yao,
"Optimization and calibration of septa-to-crystal position for a SPECT with
slit-slat collimator and pixelated crystals," IEEE Transactions on Nuclear
Science, vol. 58, No. 5, pp. 2234-2243, Oct. 2011.
12.
T. Ma, Y. Miao,
R. Yao, T. Dai and X. Deng,
"Quantitative Accuracy Assessment and Optimization of SPECT Geometrical
Calibration," Tsinghua Science and Technology, Vol. 15, pp. 96-101, 2010.
- T. Ma, R. Yao, Y. Shao, R. Zhou, "A method to
assess the uniqueness and accuracy of SPECT geometrical
calibration," IEEE Transactions on Medical Imaging, Vol. 28, No. 12,
pp.1929-1939, Dec. 2009.
- R. Yao,
T. Ma and Y. Shao, "Derivation of system matrix from simulation data for
an animal SPECT with slit-slat collimator," IEEE Transactions on Nuclear
Science, vol. 56, no.5, pp. 2651-2658, Oct. 2009.
- S. K. Pandey, M. Sajjad, Y. Chen, X. Zheng, R. Yao,
J. R. Missert, C. Batt, H. A. Nabi, A. R. Oseroff and R. K. Pandey,
"Comparative PET Imaging and Phototherapeutic Potential of 124I- Labeled
Methyl- 3-(1'-m-iodobenzyloxyethyl) pyropheophorbide-a vs. the
Corresponding Glucose- and Galactose-Conjugates," Journal of Medicinal
Chemistry, vol. 52, no.2, pp. 445-455, Jan. 2009.
- S. K. Pandey, M. Sajjad, Y. Chen, R. Yao, J.
R. Missert, C. Batt, H. A. Nabi, A. R. Oseroff and R. K. Pandey,
"124I-Labeled Purpurinimides: Impact of the Isomers in PET Imaging and
Photodynamic Therapy (PDT)," Bioconjugate Chemistry, vol. 20, no.2,
pp. 274-282, Feb. 2009.
- R. Yao,
T. Ma and Y. Shao, "Lutetium oxyorthosilicate (LSO) intrinsic activity
correction and minimal detectable target activity study for SPECT
imaging with a LSO-based animal PET scanner," Physics in Medicine and
Biology, vol. 53, pp. 4399-4415, 2008.
- Y. Shao, R. Yao and T. Ma, "A novel method to
calibrate the DOI function of a PET detector with a dual-scintillator-ends
readout," Medical Physics, vol. 35, pp. 5829-5840, December 2008.
- M. D. Jones, R. Yao, C. P. Bhole, "Parallel
OSEM Reconstruction Speed with MPI, OpenMP, and hybrid MPI-OpenMP Programming
Models", IEEE Transactions on Nuclear Science, vol. 53, pp. 2752-2758, 2006.
- R. Yao,
J. Seidel, J.-S. Liow and M. V. Green, "Attenuation Correction for the
NIH ATLAS Small Animal PET Scanner," IEEE Transactions on Nuclear
Science, vol. 52, No. 3, pp.664-668, June 2005.
- R. Yao,
J. Seidel, C.A. Johnson, M.E. Daube-Witherspoon, M.V. Green and R.E.
Carson "Factors affecting the performance of the 3D OSEM algorithm in the
reconstruction of small animal PET images," IEEE Transactions on Medical
Imaging, Volume: 19 Issue: 8, pp. 798-804, Aug. 2000.
- R. Yao,
M. Bentourkia and R. Lecomte, "Study of multispectral
frame-by-frame convolution scatter correction in high resolution
PET", IEEE Transactions on Nuclear Science, vol. 44, pp. 2489-2493,
1997.
- R. Yao,
P. Msaki and R. Lecomte, "Pre-processing variance reducing
techniques in multispectral positron emission tomography", Physics
in Medicine & Biology, vol. 42,
pp.2233-2253, 1997.
- R. Yao,
P. Msaki, M. Bentourkia and R. Lecomte, "Effects of energy space
smoothing and projection space normalization on multispectral PET image
quality", IEEE Transactions on Nuclear Science, vol. 43,
pp.1988-1994, 1996.
- R. Lecomte, J. Cadorette, S. Rodrigue, D. Rouleau, M.
Bentourkia, R. Yao and P. Msaki, "Initial results from the
Sherbrooke avalanche photodiode PET scanner", IEEE Transactions on
Nuclear Science, vol. 43, pp.1952-1957, 1996.
Honor
Prix d'Excellence, d'Innovation et d'Implication du Regroupement des
Etudiants et Etudiantes Chercheurs en Medecine de l'Universite de Sherbrooke,
Canada, 1997.
Journal Reviewer of
IEEE
Transactions on Medical Imaging, IEEE Transactions on Nuclear Sciences,
Medical Physics, Physics in Medicine and Biology, Journal of Nuclear Medicine
Technology.
Courses Taught at University at Buffalo
Nuclear Medicine Imaging, MDY 571,
Fall.
Basic Radiation Science, NMD421/BIO461, Fall.
Introduction to Molecular Imaging: PET, NMD525/PHM525, Fall.
Nuclear Medicine Imaging Physics, NMD424,
Spring.
Advanced Subjects in Nuclear Emission
Imaging, MDY 572, Spring.
Radiopharmacy, PHM587, Spring.
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