What Is CLIMB UP?
The CLIMB Undergraduate Program for Summer Research is an opportunity for undergraduate students to perform research and gain understanding of graduate career opportunities at University at Buffalo.
The goals of the program are to:
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Introduce you to research in the biomedical and pharmacological sciences
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Facilitate your understanding of recent advances in the biosciences
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Mentor you towards graduate careers in the discipline of your choice
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Guide you through novel and exciting research projects and mentored by faculty, graduate students, and postdoctoral fellows through the summer and beyond.
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HAVE FUN in Buffalo during the Summer!
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What’s On the Agenda?
CLIMB UP Summer 2013 will be held from early June 2012 through Friday August 2, 2013 (Monday-Friday 8:30-5PM).
CLICK HERE TO VIEW THE PROGRAM FOR 2012- Last updated 5/21/2012.
Highlights include...
You will spend your days in the laboratory of your research mentor, whom you will be paired with based on your research interests. We will train you in various areas necessary to safely and efficiently perform your research and related activities
Our combination of research, academic, and social activities make for an exciting and worthwhile summer experience!
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Research Rotations
CLIMB UP offers many diverse research opportunities in the areas of biomedical sciences. You will be matched with a participating faculty mentor whose interests are complementary to your own. Please research these mentors' programs (linked below), and then let us know in your application whose labs best suit your interest.
Mentors and student project titles from Summer 2012 are listed here. This will give you a sense of the type of research done in each lab. Other faculty mentors in drug discovery and related topics are listed in the links below.
| Caroline Bass, PhD |
Creating a Conditional RNAi AAV Vector |
| Derek Daniels, PhD |
The role of drinking in the behavioral desensitization observed after repeated injections of Ang II |
| Margarita L. Dubocovich, PhD |
Diurnal Expression of MT1 Melatonin Receptor Transcription in Pars Tuberalis of C3H/HeN Mice |
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Melatonin Modulation of Reward Related Learning and Memory via the MT1 and MT2 Receptors |
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Regulation of Mammalian Target of Rapamycin after Methamphetamine Treatment in C57Bl/6 Mice |
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Effects of Melatonin on Ketamine-Induced mTOR Phosphorylation in C3H/HeN Mouse Brain |
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MT1 receptor overexpression following viral injections in Ventral Tegmental Area |
| M. Laura Feltri, MD |
The Study of Integrins in Schwann Cells |
| Samir Haj-Dahmane, PhD |
Effect of Melatonin on Glutamatergic Synaptic Transmission in the Lateral Habenula |
| Te-Chung Lee, PhD |
Purification of secreted Frizzled Related Protein 2 (sFRP2) |
| Ji Li, PhD |
The Role of AMPK & MAPKs in Ameliorating Liver Dysfunction Associated with
Dietary-Induced Obesity |
| Marilyn Morris, PhD |
Functional Characterization of the Transport of Butyric Acid and γ-hydroxybutyric Acid (GHB) in Rat Kidney KNRK Cells and Human Proximal Renal Tubule Cells |
| James Olson, Ph.D. |
Analysis of PROFENOFOS Exposure in Egyptian Agricultural Workers |
| Jinwoo Park, PhD |
Regulation of Dopamine transmission by Noradrenergic Neurons in the Rat Brain |
| Rajendram Rajnarayanan, PhD |
Structural Determinants of Poly (ADP-Ribose) Polymerase Inhibition by Tetracyclines and Natural Compounds |
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Locking Human Estrogen Receptor α/ Breast Cancer Susceptibility Protein Type 1 Complex |
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Design and Synthesis of Bivalent Ligands Targeting Human Melatonin Receptors |
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Small Molecules Targeting G Protein to Combat Against Metastatic Cancer |
| Fraser Sim, PhD |
The Detection of Sprouty-1 Protein in the CG4 cell line |
| Satpal Singh, PhD |
Is Celebrex Usage Associated with an Increased Risk of Arrhythmic Events? Data Mining of the AERS Database |
| Aiming Yu, PhD |
Impact of Anticancer Drugs and Natural Compounds on microRNA expression in Cancer Cells |
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Expression of MicroRNA-1291 in various carcinoma cells |
Other research faculty are also associated with the departments listed below at UB and with various graduate programs. These faculty members (over 120 individuals) have diverse research interests encompassing virtually all aspects of modern biological, neuroscience, and biomedical science. In addition, if you are interested in a more clinical approach, we encourage you to check out the Department of Medicine or the Medical Scientist Training Program faculty. If you are interested in working with members of these departments not listed above, please let us know. We cannot guarantee placement with them, but it will help gauge your interest and make appropriate matches.
| Participating Departments include: |
Our mentors do research in areas such as: |
The School of Medicine and Biomedical Sciences
School of Dental Medicine
Hauptman-Woodward Institute
School of Pharmacy and Pharmaceutical Sciences
College of Arts and Sciences
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Neurobiology of Ingestive Behavior
Neuropharmacology
Drug Discovery
Circadian Rhythms
Cardiovascular Pharmacology
Crystallography
Cancer Treatments
Pharmaceutical Sciences
Pharmacotherapy for Pain
Drug Addiction and Abuse
Biological and Toxicological Effects of Pesticides
Genomics and Proteomics
Medicinal Chemistry
Neurodegenerative Disorders
Ion Channels
Neural Networks in the Retina
Structural Biology
Drug Metabolism and Pharmacokinetics |
In addition, during the first week in the program, students attend the Introduction to Laboratory Skills course, taught by Dr. David Shubert and Ms. Deborah Timineri, Instructional Support Associate. Students learn essential skills and important laboratory safety protocols to conduct their summer research.
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Funding
CLIMB UP offers paid internships.
Funds are available to cover a living stipend (room and board plus incidentals, paid biweekly) for a limited number of students through the generous support of:
STUDENTS WHO ARE CURRENTLY IN PROGRAMS SUCH AS THE MARC PROGRAM OR THE MCNAIR SCHOLARS PROGRAM AT THEIR HOME INSTITUTION ARE ENCOURAGED TO APPLY TO CLIMB UP. IF YOU ARE ACCEPTED, YOUR PROGRAM WILL COVER THE COST OF YOUR RESEARCH EXPERIENCE.
On-campus housing is available at low rates [limited availability]). Depending on the source of funding, the cost of housing may be deducted from the living stipend, but this is determined on a case-by-case basis.
Who Is Eligible for CLIMB UP?
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The CLIMB UP for Summer Research trains highly qualified undergraduate students interested in the biomedical sciences, and in particular pharmacology and toxicology.
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Students enrolled in the program are entering their sophomore, junior, or senior years in undergraduate programs at colleges and universities (from UB and beyond!).
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In order to qualify for funding, CLIMB UP applicants must currently be U.S. citizens or permanent residents.
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Women, persons from underrepresented minority backgrounds, and persons with disabilities are encouraged to apply.
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How Do I Apply to CLIMB UP?
Applications for 2013 will be accepted from November 21, 2012-February 1, 2013.
CLICK HERE FOR THE 2013 APPLICATION
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Applicants for The CLIMB UP for Summer Research are required to submit:
- Personal statement describing interest in research and career goals (in online application, or you may also email this part to climb@buffalo.edu)
- Please forward a copy of your most recent CV or resume to climb@buffalo.edu.
- Official grade transcripts sent to the mailing address:
The CLIMB UP for Summer Research
Liz Marshall
University at Buffalo
102 Farber Hall
3435 Main Street
Buffalo, NY 14214
- Two (2) letters of recommendation e-mailed directly to the program at climb@buffalo.edu. Please tell your referees to include in the subject line: your last name followed by a colon, and the words "CLIMB UP rec" (example, Smith:CLIMB UP rec).
We recommend that you find two people in science (preferably people who have taught you, but not always) to write you letters of recommendation. Professors are preferred, however if there are post-docs and/or graduate students who have supervised you, or can attest to your interests and talents in regards to research and/or coursework, we will certainly welcome letters from them.
If you have specific questions, please feel free to contact us.
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