Publications from the Hakansson lab

Original publications:

*Undergraduate student, ** Graduate student, ***Post-doctoral fellow or staff from my laboratory

At Lund University (1993 – 2000)

  1. Aniansson G, Alm B, Andersson B, Håkansson A, Larsson P, Nylén O, Peterson H, Rignér P, Svanborg M, Sabharwal H, Svanborg C. A prospective, cohort study on breast feeding and otitis media in Swedish infants. Pediatr. Infec. Dis. J. 1994; 13: 183-188. PMID: 8177624.
  2. Håkansson A, Kidd A, Wadell G, Sabharwal H, and Svanborg C. Adenovirus infection enhances the in vitro adherence of Streptococcus pneumoniae. Infect. Immun. 1994; 62: 2707-2714. PMID: 8005661. PMCID: PMC302872.
  3. Davies J, Carlstedt I, Nilsson A-K, Håkansson A, Sabharwal H, and Svanborg C. Binding of Haemophilus influenzae to purified mucins from the human respiratory tract. Infect. Immun. 1995; 63: 2485-2492. PMID: 7790060. PMCID: PMC173332.
  4. Håkansson A, Zhivotovsky B, Orrenius S, Sabharwal H, and Svanborg C. Apoptosis induced by a human milk protein. Proc. Natl. Acad. Sci. USA. 1995; 92: 8064-8068. PMID: 7644538. PMCID: PMC41287.
  5. Andersson von Rosen I, Håkansson A, Aniansson G, Hansson C, Andersson B, Sabharwal H, Svanborg C. Antibodies to pneumococcal polysaccharides in human milk: relationship to colonization and acute otitis media. Pediatr. Infect. Dis. J. 1996; 15: 498-507. PMID: 8783346.
  6. Perez MT, Arnér K, Håkansson A. DNA fragmentation characteristic of apoptosis and cell loss induced by kainic acid in rabbit retina. Neurochem. Internat. 1997; 31: 251-260. PMID: 9220458.
  7. Karpman D, Håkansson A, Perez M-T, Isaksson C, Caprioli A, and Svanborg C. Apoptosis of renal cortical cells in hemolytic uremic syndrome: in vivo and in vitro studies. Infect. Immun. 1998; 66: 636-644. PMID: 9453620. PMCID: PMC107951.
  8. Håkansson A, Andréasson J, Zhivotovsky B, Karpman D, Orrenius S, and Svanborg C. Multimeric a-lactalbumin from human milk induces apoptosis through a direct effect on cell nuclei. Exp. Cell Res. 1999; 246: 451-460. PMID: 9925761.
  9. Svensson M, Sabharwal H, Håkansson A, Mossberg A-K, Lipniunas P, Leffler H, Svanborg C, Linse S. Spectroscopic characterization of a-lactalbumin folding variants that induce apoptosis in tumor cells. J. Biol. Chem. 1999; 274: 6388-6396. PMID: 10037730.
  10. Köhler C#, Håkansson A#, Svanborg S, Orrenius S, and Zhivotovsky B. Protease activation in multimeric a-lactalbumin induced apoptosis. Exp. Cell Res. 1999; 249: 260-268. (#These authors share first authorship) PMID: 10366425.
  11. Håkansson A, Svensson M, Mossberg A-K, Sabharwal H, Linse S, Lazou I, Lönnerdal B, and Svanborg C. A folding variant of a-lactalbumin with bactericidal activity against Streptococcus pneumoniae. Mol. Microbiol. 2000; 35: 589-600. PMID: 10672181.
  12. Svensson M, Håkansson A, Mossberg A-K, Linse S, Svanborg C. Conversion of a-lactalbumin to a protein inducing apoptosis. Proc Natl Acad Sci USA2000; 97: 4221-4226. PMID: 10760289. PMCID: PMC18203.
  13. Köhler C, Gogvadze V, Håkansson A, Svanborg C, Orrenius S and Zhivotovsky B. A folding variant of human a-lactalbumin induces mitochondrial permeability transition in isolated mitochondria Eur J Biochem. 2001; 268: 186-191. PMID: 11121120.
  14. Mizusawa H, Hedlund P, Håkansson A, Alm P, Andersson K-E. Morphological and functional in vitro and in vivo characterization of the mouse corpus cavernosum. Br J Pharmacol 2001; 132:1333-1341. PMID: 11250885. PMCID: PMC1572671.

At University of Alabama at Birmingham (2000 – 2002)

  1. Håkansson A, Roche H**, Mizra S, McDaniel L, Brooks-Walter A and Briles DE. Characterization of the binding of human lactoferrin to pneumococcal surface protein A. Infect. Immun. 2001; 69: 3372-81. PMID: 11292760. PMCID: PMC98296.
  2. Yrlid U, Svensson M, Håkansson A, Chambers BJ, Ljunggren H-G and Wick MJ. In vivo activation of dendritic cells and T cells during Salmonella typhimurium infection. Infect. Immun. 2001; 69: 5726-35. PMID: 11500449. PMCID: PMC98689.
  3. Smith AW**, Roche H**, Trombe MC, Briles, DE and Håkansson A. Characterization of the dihydrolipoamide dehydrogenase from Streptococcus pneumoniae and its role in virulence. Mol. Microbiol. 2002; 44: 431-448. PMID: 11972781.
  4. Roche H**, Håkansson A, Hollingshead S.K., and Briles, D.E. Regions of PspA/EF3296 best able to elicit protection against Streptococcus pneumoniae in a murine infection model. Infect. Immun. 2003; 71: 1033-1041.PMID: 12595413. PMCID: PMC148823.
  5. Roche H**, Ren B, MacDaniel L, Håkansson A, and Briles, D.E. Relative roles of genetic background and variation of PspA in the ability of antibodies to PspA to protect against capsular type 3 and 4 strains of Streptococcus pneumoniae. Infect. Immun. 2003; 71: 4498-4505. PMID: 12874329. PMCID: PMC166025.

At Children’s Hospital/Harvard Medical School (2002 – 2006)

  1. Hakansson A, Cywes Bentley C, Shakhnovic E. A., and Wessels M. R. Cytolysin-dependent evasion of lysosomal killing. Proc. Natl. Acad. Sci. USA. 2005; 102: 5192-5197. DOI: 10.1073/pnas.0408721102. PMID: 15795386. PMCID: PMC555683.
  2. Cywes Bentley C, Hakansson A, Christianson J, Wessels M.R. Extracellular group A Streptococcus induces keratinocyte apoptosis by dysregulating calcium signaling. Cell Microbiol. 2005; 7: 945-955. DOI: 10.1111/j.1462-5822.2005.00525.x. PMID: 15953027.
  3. Michos A, Gryllos I, Hakansson A, Srivastava A, Kokkotou A, and Wessels MR. Enhancement of streptolysin O activity and intrinsic cytotoxic effects of the group A streptococcal toxin, NAD-glycohydrolase. J. Biol. Chem. 2006; 281: 8216-23. DOI: 10.1074/jbc.M511674200. PMID: 16431917.
  4. Daniels CC*, Briles TC*, Mirza S, Håkansson AP, and Briles DE. Capsule does not block antibody binding to PspA, a surface virulence protein of Streptococcus pneumoniae. Microbial Path. 2006; 40: 228-223. DOI: 10.1016/j.micpath.2006.01.007. PMID: 16540281.
  5. Gryllos I, Grifantini R, Colaprico A, Jiang S, DeForce E*, Hakansson A, Telford JL, Grandi G, and Wessels MR. Mg2+ signaling defines the Group A streptococcal CsrRS (CovRS) regulon. Mol Microbiol. 2007; 65: 671-83. DOI: 10.1111/j.1365-2958.2007.05818.x. PMID: 17608796.

At University at Buffalo (2007 – 2014)

  1. Hakansson AP, and Smith AW**. Enzymatic characterization of dihydrolipoamide dehydrogenase from Streptococcus pneumoniae harboring its own substrate. J Biol Chem. 2007; 282: 29521-30. DOI: 10.1074/jbc.M703144200. PMID: 17690105.
  2. Gryllos I, Grifantini R, Colaprico A, Cary ME, Hakansson A, Carey DW, Suarez-Chavez M, Kalish LA, Mitchell PD, White GL, and Wessels MR. PerR confers resistance to phagocytic killing and enhances pharyngeal colonization by group A Streptococcus. PLoS Pathogen. 2008: 4: e1000248.
    DOI: 10.1371/journal.ppat.1000145. PMID: 18773116. PMCID: PMC2518855.
  3. Logsdon L, Håkansson AP, Cortés G, and Wessels MR. Streptolysin O inhibits clathrin-dependent internalization of group A Streptococcus. MBio. 2011; 2: e00332-10. DOI: 10.1128/mBio.00332-10. PMID: 21325037. PMCID: PMC3039441.
  4. Hakansson AP, Roche-Hakansson H***, Mossberg A-K, and Svanborg C. Apoptosis-induced death in bacteria induced by HAMLET, a human milk protein-lipid complex. PLoS One 2011; 6(3): e17717. DOI: 10.1371/journal.pone.0017717. PMID: 21423701. PMCID: PMC3053380.
  5. Permyakov SE, Knyazeva EL, Leonteva MV, Fadeev RS, Chekanov AV, Zhadan AP, Hakansson AP, Akatov VS, and Permyakov ES. A novel method for preparation of HAMLET-like protein complexes. Biochimie 2011; 93: 1495-501. DOI: 10.1016/j.biochi.2011.05.002. PMID: 21596091.
  6. Tyx, RE**, Roche-Hakansson H***, and Hakansson AP. The role of dihydrolipoamide dehydrogenase in regulation of raffinose transport in Streptococcus pneumoniae. J. Bacteriol. 2011; 193: 3512-24. DOI: 10.1128/JB.01410-10. PMID: 21602335. PMCID: PMC3133304.
  7. Permyakov SE, Knyazeva EL, Khasanova LM, Fadeev RS, Zhadan AP, Roche-Hakansson-H***, Hakansson AP, Akatov VS, and Permyakov ES. Oleic acid is a key cytotoxic component of HAMLET-like complexes. Biol. Chem. 2012; 393: 85-92.DOI: 10.1515/BC-2011-230. PMID: 22628302.
  8. Marks LR**, Parameswaran GI, and Hakansson AP. Streptococcus pneumoniae Forms Biofilms During Colonization of Mice that are Phenotypically Reproduced Using Epithelial Cell Substrata in vitro. Infect. Immun. 2012; 80: 2744-60.DOI: 10.1128/IAI.00488-12. PMID: 22645283. PMCID: PMC3434590.
  9. Clementi EA**, Marks LR**, Duffey ME, and Hakansson AP. A novel death pathway in Streptococcus pneumoniae induced by the human milk protein-lipid complex HAMLET, and activated during physiological death. J. Biol. Chem 2012; 287: 27168-82.DOI: 10.1074/jbc.M112.371070. PMID: 22700972. PMCID: PMC3411059.
  10. Marks LR**, Clementi EA**, and Hakansson AP. The human milk protein-lipid complex HAMLET sensitizes bacterial pathogens to traditional antimicrobial agents. PLoS One 2012; 7: e43514.DOI: 10.1371/journal.pone.0043514. PMID: 22905269. PMCID: PMC3419703.
  11. Marks LR**, Reddinger R**, and Hakansson AP. High Levels of Genetic Recombination During Nasopharyngeal Carriage andBiofilm formation in Streptococcus pneumoniae. MBio. 2012; 3: e00200-12.DOI: 10.1128/mBio.00200-12. PMID: 23015736. PMCID: PMC3448161.
  12. Marks LR**, Clementi EA**, and Hakansson AP. Sensitization of Staphylococcus aureus to methicillin and other antibiotics in vitro and in vivo in the presence of HAMLET. PLoS One. 2013; 8: e63158.DOI: 10.1371/journal.pone.0063158. PMID: 23650551. PMCID: PMC3641093
    (Commentary by Science Magazine: ScienceNOW (May 1, 2013)
  13. Marks LR**, Davidson BA, Knight PR, and Hakansson AP. Interkingdom signaling induces Streptococcus pneumoniae biofilm dispersion and transition from asymptomatic colonization to disease. MBio. 2013; 4: e00438-13.DOI: 10.1128/mBio.00438-13. PMID: 23882016 PMCID: PMC3735180.
    (Highlighted in Nature. 2013: 500:124)
  14. Clementi EA**#, Wilhelm KR#, Schleucher J, Morozova-Roche, LA, and Hakansson AP. A complex of equine lysozyme and oleic acid with bactericidal activity against Streptococcus pneumoniae. PLoS One. 2013; 8: e80649. (#These authors share first authorship.)DOI: 10.1371/journal.pone.0080649. PMID: 24260444. PMCID: PMC3832479.
  15. Clementi CF**, Hakansson AP, and Murphy TF. Internalization and trafficking of nontypeable Haemophilus influenzae in human respiratory epithelial cells, and the roles of IgA1 proteases, IgaA and IgaB, for optimal internalization and persistence. Infect. Immun. 2014; 82: 433-44. DOI: 10.1128/IAI.00864-13. PMID: 24218477. PMCID: PMC3911862.
  16. Marks LR**, Reddinger RM**, and Hakansson AP. Biofilm formation enhances fomite survival of Streptococcus pneumoniae and Streptococcus pyogenes. Infect. Immun. 2014: 82: 1141-1146. DOI: 10.1128/IAI.01310-13. PMID: 24371220. PMCID: PMC3957990.
    (Commentary by New Engl J Med)
  17. Rath EM**, Duff AP, Hakansson AP, Knott RB, and Church WB. Small-angle X-ray scattering of BAMLET at pH 12: a complex of a-lactalbumin and oleic acid. Protein: Structure, Function and Bioinformatics. 2014; 82: 1400-1408.DOI: 10.1002/prot.24508. PMID: 24408789. PMCID: In process.
  18. Marks LR**, Mashbburn-Warren L, Federle MJ, and Hakansson AP. Streptococcus pyogenes biofilm growth in vitro and in vivo and its relationship to colonization, virulence, and genetic exchange. J. Infect. Dis. 2014; 210: 25-34.DOI: 10.1093/infdis/jiu058. PMID: 24465015. PMCID: PMC4162002(Provided cover art for the issue of the Journal)
  19. Clementi EA**#, Marks LR**#, Roche-Hakansson H***, and Hakansson AP. Fluorescence-based measurements of membrane depolarization, rupture and ion fluxes in Streptococcus pneumoniae. JoVE 2014; 84: e51008. (#These authors share first authorship.) DOI: 10.3791/51008. PMID: 24637356. PMCID: In process.
  20. Jones CH**, Ravikrishnan A, Rane S, Ahmadi MK, Chen CK, Cheng C, Smith R, Andreadis S, Hakansson AP#, Pfeifer BA#. Hybrid bio-synthetic gene therapy vector development and dual engineering capacity. Proc. Natl. Acad. Sci. USA 2014; 111: 12360-5. (#These authors share senior authorship)DOI: 10.1073/pnas.1411355111. PMID: 25114239. PMCID: PMC4151754.
  21. Pettigrew MM, Marks LR**, Kong Y, Gent J, Roche-Hakansson H***, and Hakansson AP. Variation in the Streptococcus pneumoniae transcriptome in transition from biofilm formation to invasive disease. Infect. Immun.2014; 82: 4607-19.DOI: 10.1128/IAI.02225-14. PMID: 25135685. PCMID: PMC4249342.
  22. Jones CH**, Chen M, Ravikrishnan A, Reddinger RM**, Zhang G, Hakansson AP, and Pfeifer BA. Mannosylated poly(beta-amino esters) for targeted antigen presenting cell immune modulation. Biomaterials. 2014; 37C: 333-344.DOI: 10.1016/j.biomaterials.2014.10.037. PMID: 25453962.

At Lund University (2014 –):

  1. MacDonald B, Chakravarthy K, Davidson B. Mullan B, Alluri R, Hakansson AP, Knight PR III. Halothane Modulates the Type I Interferon Response to Influenza and Minimizes the Risk of Secondary Bacterial Pneumonia through Maintenance of Neutrophil Recruitment in an Animal Model. Anesthesiology. 2015; 123: 590-602. DOI: 10.1097/ALN.0000000000000766 PMID: 26120770. PMCID: PMC4678100.
  2. Thamadilok S, Roche-Hakansson H***, Hakansson AP, and Ruhl S. Absence of Capsule Reveals Glycan-Mediated Binding and Recognition of Salivary Mucin MUC7 by Streptococcus pneumoniae. Mol. Oral Microbiol. 2015; 31: 175-188. DOI: 10.1111/omi.12113. PMID: 26172471. PMCID: PMC4713356.
  3. Greene CJ, Marks LR**, Hu JC, Reddinger RM**, Mandell, L., Roche-Hakansson H***, King-Lyons ND, Connell TD, and Hakansson AP. A novel strategy to protect against influenza-induced pneumococcal disease without interfering with commensal colonization. Infect. Immun. 2016; 84: 1693. DOI:10.1128/IAI.01478-15. PMID: 27001538. PMCID: PMC4907141.
  4. Li Y, Hill A, Beitelshees M, Shao S, Lovell JF, Hakansson AP#, Pfeifer BA#, Jones CH***#. Directed vaccination against pneumococcal disease. Proc. Natl. Acad. Sci. USA2016; 111: 12360-5. (# These authors share senior authorship)DOI: 10.1073/pnas.1603007113. PMID: 27274071. PMCID: PMC4922154.
  5. Li Y, Beitelshees M, Fang L, Hill A, Kamal Ahmadi M, Chen M, Davidson B, Knight P, Hakansson AP, Jones CH***, Pfeifer B. In situ pneumococcal vaccine production and delivery through a hybrid vector. Sci. Adv. 2016; 2: e1600264.DOI: 10.1126/sciadv.1600264. PMID: 27419235. PMCID: PMC4942325.
  6. Reddinger RM**, Luke-Marshall NR, Hakansson AP, and Campagnari AA. Host physiologic changes induced by influenza A virus leads to Staphylococcus aureus biofilm dispersion and transition from asymptomatic colonization to invasive disease. MBio. 2016; 7: e01235-16. DOI: 10.1128/mBio.01235-16. PMID: 27507829. PMCID: PMC4981728.
    (Selected for ASM Journal Press release).
  7. Roche-Hakansson H***, Vansarla G**, Metzger DJ*, Mossberg AK***, and Hakansson AP. Role of glycolysis during Streptococcus pneumoniae death induced by the human milk protein-lipid complex HAMLET. J. Biol. Chem. 2017 (Resubmitted after major revision).
  8. Rath EM**, Cheng YY, Sarun K, Hudson AL, Weir C, Wang Y, Hakansson AP, Howell V, Liu GJ, Reid G, Knott RK, Duff AP, and Church WB. BAMLET is cytotoxic towards chemotherapy-resistant mesothelioma, holding oleic acid in an actively cytotoxic state. J Mol Biol. 2017 (submitted).

B. Reviews / Book chapters (invited, peer-reviewed):

  1. Håkansson A, Nilsson A-K, Davies J, Carlstedt I, Sabharwal H, Svanborg C. Interactions of Haemophilus influenzae and Streptococcus pneumoniae with the respiratory tract mucosa. Am. J. Respir. Critical Care Med. 1996; 154 (suppl): S187-191. DOI: 10.1164/ajrccm/154.4_Pt_2.S187. PMID: 8876540.
  2. Håkansson A, Blomberg J, Svanborg C, and Sabharwal H. Virally enhanced bacterial adherence to a respiratory tract cell line in vitro. In: Recent advances in otitis media. Editors: Mogi G, Honjo I, Ishii T, and Takasaka T. Kugler Publications, New York, USA. 1996.
  3. Svensson M, Düringer C, Hallberg O, Mossberg A, Håkansson A, Linse S, and Svanborg CHAMLET – a complex from human milk that induces apoptosis in tumor cells but spares healthy cells.Adv Exp Med Biol. 2002; 503: 125-132. PMID: 12026011
  4. Hakansson AP, Marks LR**, Roche-Hakansson H***. Pneumococcal genetic recombination during colonization and biofilm formation. In “Streptococcus pneumoniae: Molecular mechanisms of host-pathogen interactions,” Edited by Drs. Carlos Orihuela, Sven Hammerschmidt, and Jeremy Brown. 2015; Chapter 7; 129-142. Elsevier, Academic Press, London, UK.
  5. Jones CH**, Hakansson AP, Pfeifer BA. Biomaterials at the interface of nano- and micro-scale vector-cellular interactions in genetic vaccine design. J Mater Chem B. 2014; 2: 8053-8068. DOI: 10.1039/C4TB01058B
  6. Chao Y**, Marks LR**, Pettigrew MM, Hakansson AP. Streptococcus pneumoniae biofilm formation and dispersion during colonization and disease. Frontiers Cell Infect Microbiol. 2015; 4: 194 (1-16). DOI: 10.3389/fcimb.2014.00194. PMID: 25629011. PMCID: PMC4292784
  7. Rath EM**, Duff AP, Hakansson AP, Vacher CS, Jun Liu G, Knott RB, and Church WB. Structure and potential cellular targets of HAMLET-like anti-cancer compounds made from milk components. In Special issue: “Natural Products: Biochemical-Chemical Characterization, and Evidence for Therapeutic Potential” J Pharmacy Pharmaceutical Sci. 2015; 18: 773-824. PMID: 26626257. PMCID: In process.
  8. Barenkamp SJ, Hakansson AP, Heikkinen T, King S, Nosko-Koivisto J, Novotny, LA, Patel, JA, Pettigrew MM, and Swords WE Chonmaitree T. Panel 4: Bacteriology and Virology. Otolaryngol Head Neck Surg. Supplement 2017 (In press).
  9. Pettigrew MM, Alderson MR, Bakaletz LO, Barenkamp SJ, Hakansson AP, Mason KM, Nosko-Koivisto J, Patel JA, Pelton SI, and Murphy TF. Panel 6: Vaccines. Otolaryngol Head Neck Surg. Supplement 2017 (In press).
  10. Chao Y**, Bergenfelz C***, and Hakansson AP. Chapter 19: In vitro and in vivo biofilm formation by pathogenic streptococci. InBacterial Pathogenesis: Methods and Protocols” edited by Pontus Nordenfelt and Mattias Collin. Methods Mol Biol 2017; 1535: 285-299. DOI: 10.1007/978-1-4939-6673-8_19. DOI: 10.1007/978-1-4939-6673-8_19. PMID: 27914087. PMCID: In progress.
  11. Bergenfelz C***, and Hakansson AP. Streptococcus pneumoniae otitis media pathogenesis nd how it informs our understanding of vaccine strategies. Curr. Otorhinolaryngol. Rep. 2017 (In press).
  12. Gardelii A*#, Hassan KO*#, and Hakansson AP. Non-antibiotic sensitizing agents that restore antibiotic resistance. In: “Antibiotic drug resistance”. Edited by Drs. Ramaiah Muthyala (Editor-in chief), José Luis Capelo, Yuk Yin Sham, and Gilberto Igrejas. 2017; Chapter 4.7. John Wiley & Sons Inc., New Jersey, USA. (2017, In press).

C. Editorials (invited):

  1. Hakansson AP. Pneumococcal Adaptive Responses to Changing Host Environments. J. Infect Dis. 2014; 210: 1-2. (Published February 4, 2014). Editorial commentary of Syk et al. “Emergence of hyper-virulent mutants resistant to early clearance during systemic serotype 1 pneumococcal infection in mouse and man.” J. Infect. Dis. 2014: 210: 4-13. DOI: 10.1093/infdis/jiu084. PMID: 24511096.
  2. Hakansson AP. Protective effects of human milk antimicrobial peptides against bacterial infection. J. Pediatria. 2014; pii: S0021-7557(14)00145-4. Editorial commentary of Baricelli et al. Beta-defensin-2 in breast milk display activity against pathogenic bacteria. J. Pediatria. 2014. DOI: 10.1016/j.jped.2014.10.001. PMID: 25458872.  
  3. Hakansson AP, and Bergenfelz, C***. Strain-specific activation of inflammation determines fate of pneumococcal disease.  J. infect Dis. 2017 (In press). Editorial commentary of Coleman et al. The capacity of pneumococci to activate macrophage NF-κB determines necroptosis and pneumonia severity. J. Infect. Dis. 2017. DOI: 10.1093/infdis/jix161. PMID:

D. Conference proceedings:

  1. Svanborg C, Håkansson A, Nilsson A-K, Saraf A, Sabharwal H. Receptor analogues for the prevention of microbial colonization. In: 104th Ross Conference on Pediatric Research. Ross Products Division. 1994 pp. 65-73.
  2. Håkansson A, Zhivotovsky B, Orrenius S, Svanborg C. Apoptosis induced by Streptococcus pneumoniae in respiratory epithelial cells in vitro. Clin. Immunol. Immunopathol. 1995; 76 (Pt 2): Abstract 502.
  3. Nilsson A-K, Davies J, Håkansson A, Carlstedt I, Svanborg C, Sabharwal H. Binding of Haemophilus influenzae to purified mucins from the human respiratory tract. Clin. Immunol. Immunopathol. 1995; 76 (Pt 2): Abstract 506.
  4. Briles DE, Håkansson A, Roche H**, Hollingshead SK.  New vaccines for non-serotype-dependent protection against pneumococcal diseaseThird International Symposium on Antimicrobial Agents and Resistance.  pp. 327-334. 2001.
  5. Pfeifer BA, Jones C**, and Hakansson AP.  Hybrid Biological-Biomaterial Gene Delivery Vector Development and Dual Engineering Potential. EMBS Micro and Nanotechnology in Medicine Conference, IEEE Engineering in Medicine and Biology Society. 2014. Submission 103.
  6. Jones C**, Ravikrishnan A, Chen M, Reddinger RM**, Ahmadi M, Rane S, Hakansson AP, and Pfeifer BA. “Hybrid bio-synthetic gene therapy vector development for next generation vaccines”. EMBS Micro and Nanotechnology in Medicine Conference, IEEE Engineering in Medicine and Biology Society. 2014. Submission 104.
  7. Mansour M*, Poten A, Hakansson A, and Dejmek A. HAMLET – A promising novel marker of malignancy in effusion. 39th European Congress of Cytopathology, Milan, Italy, 20 – 23 September 2015. Cytopathology. 2015; 26 (Suppl. 1): 30. Abstract FP7-1.

Theses from the laboratory:

Hakansson AP. PhD. 1999. Apoptosis induced by a human milk protein complex.
Lund University, Lund, Sweden. DOWNLOAD PDF

Smith AW. 2001. PhD. Co-mentor. "Identification and characterization of the dihydrolipoamide dehydrogenase of Streptococcus pneumoniae and its role in virulence". University of Alabama at Birmingham, Birmingham, AL. DOWNLOAD PDF

Roche H. 2002. PhD. Co-mentor. "Characterization of the protective antibody responses to PspA in Streptococcus pneumoniae".
University of Alabama at Birmingham, Birmingham, AL. DOWNLOAD PDF

Tyx RE. 2011. Ph.D. Mentor. “Dihydrolipoamide dehydrogenase: A regulator of ABC transport in Streptococcus pneumoniae.” Microbiology Graduate Program, University at Buffalo, SUNY, Buffalo, NY.

Clementi EA. 2013. Ph.D. Mentor. “Mechanistic insights into death induced by protein-lipid complexes in Streptococcus pneumoniae.” Microbiology Graduate Program, University at Buffalo, SUNY, Buffalo, NY.

Marks LR. 2013. Ph.D. Mentor. “Insights into colonization, transformation, and the transition to disease of Streptococcus pneumoniae and possible targets for therapeutic intervention.” Microbiology Graduate Program, University at Buffalo, SUNY, Buffalo, NY.

Clementi CF. 2013. Ph.D. Co-mentor. “Internalization and trafficking of nontypeable Haemophilus influenzae in human respiratory epithelial cells  and the role of IGA1 proteases for optimal internalization and persistence.” Department of Microbiology and Immunology. School of Medicine and Biomedical Sciences, University at Buffalo, SUNY.