Daniel Amsterdam, Ph.D.


School of Medicine, University at Buffalo
         Professor, Departments of Microbiology, Pathology, and Medicine

Erie County Medical Center Healthcare Network
         Director, Department of Laboratory Medicine

Research Interests | Selected References | Clinical Lab Services | Antimicrobial Susceptibility Data

Research Interests

Research is focused on the clinical aspects of microbiology. Molecular and immunologic methods are used to detect and characterize emerging and reemerging microbial agents of infection, particularly Chlamydia and Mycobacterium tuberculosis. The role of cytomegalovirus infection in transplantation has been extensively studied. Additional interests include the changing patterns of resistance of gram-negative and gram-positive microorganisms to antimicrobial agents. Methods for detecting and monitoring the susceptibility (resistance) of these organisms in conventional and automated systems have been developed and are the basis for ongoing studies.

Selected References

Antimicrobial Susceptibility
Hardy, D., Amsterdam, D., Mandell, L. A., and Rotstein, C. Comparative in vitro activities of ciprofloxacin, gemifloxacin, grepafloxacin, moxifloxacin, ofloxacin, sparfloxacin, trovafloxicin, and other antimicrobial agents against bloodstream isolates of gram-positive cocci. Antimicrob. Agenst Chemother. 44:802-805, 1999.

Amsterdam, D. Susceptibility testing of antimicrobials in liquid media. In Antibiotics in Laboratory Medicine, Fourth Edition, V. Lorian (ed.), pp. 52-111, Williams & Wilkins, Baltimore, MD, 1996.

Amsterdam, D. Susceptibility. In Encyclopedia of Microbiology, Volume 4, J. Lederberg (ed.), pp. 157-163, Academic Press, New York, NY, 1992.

Amsterdam, D. Instrumentation for antimicrobic susceptibility testing: Yesterday, today, and tomorrow. Diagn. Microbiol. Infect. Dis. 9: 167-178, 1988.

Amsterdam, D. Principles of antibiotic testing in the laboratory. In: Laboratory Diagnosis of Infectious Diseases Principles and Practice. Volume I, Bacterial, Mycotic and Parasitic Diseases. A. Balows, W.J. Hausler, Jr., M. Ohashi and A. Turano (eds.), pp. 22-38, Springer-Verlag, New York, 1988.

Myers, J.B. and Amsterdam, D. The laboratory diagnosis of cytomegalovirus infections. Immunological Investigations 26(3):383-394, 1997.

Murray, B.M., Amsterdam, D., Gray, V., Myers, J., Gerbasi, J., and Venuto, R.C. Monitoring and diagnosis of cytomegalovirus infection in renal transplantation. J. Am. Soc. Nephrol. 8:1448-1457, 1997.

Murray, B.M., Brentjens, J., Amsterdam, D., Myers, J., Gray, V., Pawlowski, I., Schewegler, K., Singh, J.P., and Venuto, R.C. The cytomegalovirus-antigenemia assay in the diagnosis of posttransplant cytomegalovirus infection. J. Am. Soc. Nephrol. 4:1615-1622, 1994.

Mylotte, J.M. and Amsterdam, D. Tuberculosis: An overview. Clin. Lab. Sci. 9:202-206, 1996.

Amsterdam, D. Tuberculosis: The laboratory diagnosis of tuberculosis in a period of resurgence; challenge for the laboratory. Clin. Lab Sci. 9:207-212, 1996.
Fakih, M., Chapalamadugu, S., Ricat, A., Corriere, N., and Amsterdam, D. Mycobacterium malmoense bacteremia in two AIDS patients. J. Clin. Microbiol. 34:731-733, 1996.

Molecular and Immunologic Diagnosis of Disease
Immunological and molecular diagnosis of infectious disease, Proceedings of the Thirteenth International Convocation on Immunology, Buffalo, NY, June 1-5, 1996. In Immunological Investigations, Vol. 26(1&2), D. Amsterdam, R.K. Cunningham, and C.J. van Oss (eds.), pp. 1-295, Marcel Dekker, Inc., New York, NY, 1997.

Amsterdam, D. Infections associated with immunodeficiency and immunosuppression. In Topley & Wilson's Microbiology and Microbiological Infections, 9th Edition, Volume 3, Bacterial Infections. Arnold, London. 1998.